74331-69-4 Usage
Description
1-Ethynyl-4-methoxy-2-methylbenzene is an aromatic acetylene derivative characterized by its unique molecular structure, which includes an ethynyl group and a methoxy group attached to a methylbenzene backbone. 1-Ethynyl-4-methoxy-2-methylbenzene is known for its potential in chemical reactions and applications in various industries.
Uses
Used in Pharmaceutical Industry:
1-Ethynyl-4-methoxy-2-methylbenzene is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a key component in the preparation of complex molecules with potential therapeutic applications.
Used in Chemical Synthesis:
1-Ethynyl-4-methoxy-2-methylbenzene is used as a starting material for the preparation of 5-chloro-3-[(4-methoxy-2-methylphenyl)ethynyl]pyridin-2-amine, which is an important compound in the development of new drugs and pharmaceuticals. Its ethynyl and methoxy groups provide opportunities for further functionalization and modification, making it a versatile building block in organic synthesis.
Used in Research and Development:
Due to its unique structure and reactivity, 1-Ethynyl-4-methoxy-2-methylbenzene is also used in research and development for exploring new chemical reactions and understanding the properties of acetylene derivatives. Its reaction with 2-diazo-5,5-dimethylcyclohexanedione (diazodimedone) to afford cycloadducts is an example of the type of research that can be conducted using this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 74331-69-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,3,3 and 1 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 74331-69:
(7*7)+(6*4)+(5*3)+(4*3)+(3*1)+(2*6)+(1*9)=124
124 % 10 = 4
So 74331-69-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H10O/c1-4-9-5-6-10(11-3)7-8(9)2/h1,5-7H,2-3H3
74331-69-4Relevant articles and documents
Synthesis of meta and para-substituted aromatic sulfonate derivatives of polydentate phenylazaphosphinate ligands: Enhancement of the water solubility of emissive europium(III) EuroTracker dyes
Delbianco, Martina,Lamarque, Laurent,Parker, David
, p. 8061 - 8071 (2014)
The synthesis is described of a series of meta and para-substituted phenylsulfonate derivatives of very bright Eu(III) complexes with arylphosphinate groups and strongly absorbing arylalkynylpyridine moieties. The synthetic route involved the early introduction of trifluoroethyl esters to protect the sulfonic acid group, withstanding the use of reagents including acetyl bromide and mCPBA, and tolerating acid-catalysed esterification and Sonogashira reaction conditions. The Eu(III) complexes exhibit enhanced water solubility; their photophysical properties are not perturbed significantly by introduction of the anionic sulfonate groups.
Aerobic oxynitration of alkynes with tBuONO and TEMPO
Dutta, Uttam,Maity, Soham,Kancherla, Rajesh,Maiti, Debabrata
supporting information, p. 6302 - 6305 (2015/02/19)
An efficient method for stereoselective nitroaminoxylation of alkyne has been reported. The reaction enjoys a broad substrate scope, good functional group tolerance, and high yields. Synthetically useful α-nitroketones can be accessed through these products in a single step.
Cobalt-mediated total synthesis of steroids. The A → BCD approach by enediyne cyclization
Sternberg,Vollhardt
, p. 1574 - 1583 (2007/10/02)
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