7438-09-7

Basic information

• Product Name: N-methyltetradecanamide
• Synonyms: N-Methyltetradecanamide; tetradecanamide, N-methyl-
• CAS NO: 7438-09-7
• Molecular Formula: C₁₅H₃₁NO
• Molecular Weight: 241.4127
• Mol File: 7438-09-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 316.1°C at 760 mmHg
• Flash Point: 193.8°C
• Density: 0.855g/cm³
• Vapor Pressure: 0.000419mmHg at 25°C
• Refractive Index: 1.445
• CAS DataBase Reference: N-methyltetradecanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyltetradecanamide(7438-09-7)
• EPA Substance Registry System: N-methyltetradecanamide(7438-09-7)

Safety Data

• Hazardous Substances Data: 7438-09-7(Hazardous Substances Data)

Upstream product

• 112-64-1 tetradecanoyl chloride 
• 74-89-5 methylamine 
• 147642-78-2 N-benzyl-N-methyltetradecanamide 
• 544-63-8 n-tetradecanoic acid 
• 67-56-1 methanol 
• 638-58-4 tetradecanamide 
• 629-63-0 myristonitrile 

Downstream Products

• 16514-82-2 N-Methyl-N-nitrosomyristamide 
• 5338-53-4 1-morpholino-1-oxotetradecane 
• 638-58-4 tetradecanamide 
• 29369-63-9 N-methyltetradecylamine 

Relevant articles and documents

Atom-Economical and Tandem Conversion of Nitriles to N-Methylated Amides Using Methanol and Water

A cobalt complex catalyzed tandem conversion of nitrile to N-methylated amide is described using a methanol and water mixture. Using this protocol, several nitriles were directly and efficiently converted to the desired N-methylated amides. Kinetic experiments using H2O18 and CD3OD suggested that water and methanol were the source of the oxygen atom and methyl group, respectively, in the final N-methylated amides. Importantly, the participation of active Co(I)-H species in this transformation was realized from the control experiment. The kinetic isotope effect (KIE) study suggested that the activation of the C-H bond of methanol was a kinetically important step. The Hammett plot confirmed that the reaction was faster with the electron deficient nitriles. In addition, the plausible pathway for the formation of N-methylated amides from the nitriles was supported by the computational study.

Lipase-catalyzed transformations using poly(ethylene glycol) as solvent

Candida antarctica lipase catalyzes a number of elementary reactions like alcoholysis, ammoniolysis and aminolysis in poly(ethylene glycol) (PEG) media. Reaction rates were comparable to or better than those observed in conventional organic reaction media and ionic liquids. It is envisaged that PEGs could have added benefits for performing biotransformations with highly polar substrates, which are sparingly soluble in common organic solvents.