74405-00-8

Basic information

• Product Name: 4H-1,3-Benzoxazin-4-one, 3-(4-chloro-2-pyridinyl)-2,3-dihydro-2,2-dimethyl-
• Synonyms: 4H-1,3-Benzoxazin-4-one, 3-(4-chloro-2-pyridinyl)-2,3-dihydro-2,2-dimethyl-;3-(4-chloro-2-pyridinyl)-2,3-dihydro-2,2-dimethyl- 4H-1,3-Benzoxazin-4-one
• CAS NO: 74405-00-8
• Molecular Formula: C₁₅H₁₃ClN₂O₂
• Molecular Weight: 288.73
• Mol File: 74405-00-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 452.882°C at 760 mmHg
• Flash Point: 227.695°C
• Appearance: /
• Density: 1.297g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.597
• CAS DataBase Reference: 4H-1,3-Benzoxazin-4-one, 3-(4-chloro-2-pyridinyl)-2,3-dihydro-2,2-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,3-Benzoxazin-4-one, 3-(4-chloro-2-pyridinyl)-2,3-dihydro-2,2-dimethyl-(74405-00-8)
• EPA Substance Registry System: 4H-1,3-Benzoxazin-4-one, 3-(4-chloro-2-pyridinyl)-2,3-dihydro-2,2-dimethyl-(74405-00-8)

Safety Data

• Hazardous Substances Data: 74405-00-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H13ClN2O2/c1-15(2)18(13-9-10(16)7-8-17-13)14(19)11-5-3-4-6-12(11)20-15/h3-9H,1-2H3

Upstream product

• 1124-33-0 4-nitraminopyridine N-oxide 
• 74405-07-5 4-chloro-2,2-dimethyl-2H-benzo[e][1,3]oxazine 

Downstream Products

• 19798-80-2 2-Amino-4-chloropyridine 

Relevant articles and documents

Studies on 1,3-Benzoxazines. I. Synthesis of Primary 2-Amino-pyridines via the Reaction of Imidoyl Chlorides of 1,3-Benzoxazines with Pyridine N-Oxides

A new synthetic method for primary 2-aminopyridine derivatives is described.Treatment of the imidoyl chlorides of 1,3-benzoxazines (1a-i) with pyridine N-oxides resulted in the introduction of an oxazine moiety into the α-position of the pyridine ring through rearrangement of the initially formed reaction adduct.Acid hydrolysis of the rearrangement products afforded 2-aminopyridine derivatives in excellent yields.When methoxypyridine N-oxides were used, products of a different type (10 and 14) were obtained.