74421-26-4Relevant articles and documents
Catalyst-Controlled 1,2- and 1,1-Arylboration of α-Alkyl Alkenyl Arenes
Bergmann, Allison M.,Dorn, Stanna K.,Smith, Kevin B.,Logan, Kaitlyn M.,Brown, M. Kevin
supporting information, p. 1719 - 1723 (2019/01/14)
Two methods are reported for the 1,2- and 1,1-arylboration of α-methyl vinyl arenes. In the case of 1,2-arylboration, the formation of a quaternary center occurred through a rare cross-coupling reaction of a tertiary organometallic complex. 1,1-Arylboration was enabled by catalyst optimization and occurred through a β-hydride elimination/reinsertion cascade. Enantioselective variants of both processes are presented as well as mechanistic investigations.
Cyclic peptide antifungal agents
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, (2008/06/13)
Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula I STR1 where: R', R", R'", Rx1, Rx2, Ry1, Ry2, Ry3, Ry4, and R0 are as defined hereinabove; and R2 is STR2 R3 is STR3 R3a is C1 -C6 alkyl or C1 -C6 alkoxy; R3b and R3c are independently phenyl or naphthyl; R3d is C1 -C12 alkyl, C1 -C12 alkoxy or --O --(CH2)m -[O--(CH2)n ]p --O--(C1 -C12 alkyl); m is 2, 3 or 4; n is 2, 3 or 4; p is 0 or 1; or a pharmaceutically acceptable salt thereof.
