74422-90-5

Basic information

• Product Name: Benzaldehyde, 2,5-dimethoxy-3-nitro-
• CAS NO: 74422-90-5
• Molecular Formula: C9H9NO5
• Molecular Weight: 211.174
• Mol File: 74422-90-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2,5-dimethoxy-3-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2,5-dimethoxy-3-nitro-(74422-90-5)
• EPA Substance Registry System: Benzaldehyde, 2,5-dimethoxy-3-nitro-(74422-90-5)

Safety Data

• Hazardous Substances Data: 74422-90-5(Hazardous Substances Data)

Upstream product

• 85432-87-7 2-bromo-3,6-dimethoxybenzaldehyde 
• 672-13-9 2-hydroxy-5-methoxybenzaldehyde 
• 7697-37-2 nitric acid 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 34549-69-4 3-nitro-5-methoxysalicylaldehyde 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 

Downstream Products

• 1617498-52-8 C₂₅H₃₂BF₂N₃O₂ 
• 1617498-57-3 8-(3-azido-2,5-dimethoxyphenyl)-2,6-diethyl-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene 

Relevant articles and documents

Total Synthesis and Structural Revision of Clavilactone D

A structural revision of clavilactone D, a potent inhibitor of protein tyrosine kinases, was achieved by total syntheses of two newly proposed structures. The syntheses relied on ring-opening/ring-closing metathesis, which transformed a cyclobutenecarboxylate into a γ-butenolide. The syntheses confirmed that the correct structure of clavilactone D has an amino group at C-3 instead of a hydroxy group at C-2 in the originally proposed structure.

A practical synthesis of the ansa chain of benzenic ansamycin antibiotics: Total synthesis of an ansatrienol derivative

A practical and stereocontrolled synthetic approach towards the ansa chain of the benzenic ansamycins (mycotrienins) is described, which can be scaled up to multigram quantities. Key features of the synthesis are the formation of the Z-configured tri-subs

Asymmetric synthesis of the benzoquinoid ansamycin antitumor antibiotics: Total synthesis of (+)-macbecin

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