744253-75-6

Basic information

• Product Name: N-(tert-butoxycarbonyl)-(4R)-(3,5-dimethylphenylaminocarbonyloxy)-L-proline
• Synonyms: N-(tert-butoxycarbonyl)-(4R)-(3,5-dimethylphenylaminocarbonyloxy)-L-proline
• CAS NO: 744253-75-6
• Molecular Weight: 378.425
• Mol File: 744253-75-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(tert-butoxycarbonyl)-(4R)-(3,5-dimethylphenylaminocarbonyloxy)-L-proline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(tert-butoxycarbonyl)-(4R)-(3,5-dimethylphenylaminocarbonyloxy)-L-proline(744253-75-6)
• EPA Substance Registry System: N-(tert-butoxycarbonyl)-(4R)-(3,5-dimethylphenylaminocarbonyloxy)-L-proline(744253-75-6)

Safety Data

• Hazardous Substances Data: 744253-75-6(Hazardous Substances Data)

Upstream product

• 54132-75-1 3,5-dimethylphenyl isocyanate 
• 13726-69-7 (2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid 

Downstream Products

• 744253-77-8 N-(3,5-dinitrobenzoyl)-(4R)-(3,5-dimethylphenylaminocarbonyloxy)-L-proline 
• 744253-79-0 N-(3,5-dimethylbenzoyl)-(4R)-(3,5-dimethylphenylaminocarbonyloxy)-L-proline 
• 744253-76-7 N-(tert-butoxycarbonyl)-N'-(3,5-dimethylphenyl)-(4R)-(3,5-dimethylphenylaminocarbonyloxy)-L-prolinamide 
• 744253-84-7 (4R)-(3,5-dimethylphenylaminocarbonyloxy)-L-proline 

Relevant articles and documents

Synthetic studies on L-proline and (4R)-hydroxy-L-proline derivatives

The preparation of a number of L-proline and (4R)-hydroxy-L-proline derivatives to assess their enantioselectivity when applied to several techniques and experimental conditions is described. All the derivatives prepared incorporated at least one 3,5-disubstituted aromatic ring that contained nitro, chloro or methyl groups and were obtained by classical methods. In spite of the difficulties that arise from the presence of rotational isomers in most cases, the compounds studied are fully described by their 1H and 13C NMR spectra.