7443-72-3 Usage
Description
13-Ethyl-3-methoxygona-1,3,5(10),8-tetraen-17beta-ol is a chemical compound with the molecular formula C22H32O2. It is a steroidal compound derived from gonane, a steroid nucleus, and is characterized by the presence of an ethyl group at the 13th position and a methoxy group at the 3rd position. 13-Ethyl-3-methoxygona-1,3,5(10),8-tetraen-17beta-ol plays a significant role in the synthesis of various pharmaceutical agents due to its unique structural features.
Uses
Used in Pharmaceutical Industry:
13-Ethyl-3-methoxygona-1,3,5(10),8-tetraen-17beta-ol is used as a reactant in the synthesis of new immunogens for levonorgestrel, a synthetic progestin hormone. Levonorgestrel is widely used in contraceptives, hormone replacement therapy, and treatment of certain gynecological conditions. 13-Ethyl-3-methoxygona-1,3,5(10),8-tetraen-17beta-ol is also used in the synthesis of its 3-syn and anti-oximes, which are important intermediates in the development of novel pharmaceutical agents with potential applications in various therapeutic areas.
In the synthesis of new immunogens, 13-Ethyl-3-methoxygona-1,3,5(10),8-tetraen-17beta-ol serves as a key building block, providing the necessary structural features required for the development of immunogenic compounds. These immunogens can be used to stimulate the immune system to produce a specific immune response, which can be beneficial in the treatment of various diseases and conditions.
Furthermore, the compound's unique structural properties make it a valuable asset in the development of new drugs with improved efficacy, safety, and pharmacokinetic profiles. By incorporating this compound into the synthesis process, researchers can potentially create novel pharmaceutical agents with enhanced therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 7443-72-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,4 and 3 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 7443-72:
(6*7)+(5*4)+(4*4)+(3*3)+(2*7)+(1*2)=103
103 % 10 = 3
So 7443-72-3 is a valid CAS Registry Number.
InChI:InChI=1/C20H26O2/c1-3-20-11-10-16-15-7-5-14(22-2)12-13(15)4-6-17(16)18(20)8-9-19(20)21/h5,7,12,18-19,21H,3-4,6,8-11H2,1-2H3/t18-,19-,20-/m0/s1
7443-72-3Relevant articles and documents
Total synthesis with a chirogenic opening move demonstrated on steroids with estrane or 18a-homoestrane skeleton
Quinkert,Del Grosso,Doring,Doring,Schenkel,Bauch,Dambacher,Bats,Zimmermann,Durner
, p. 1345 - 1391 (2007/10/02)
A concept of first choice for the synthesis of the title compounds had been proposed by Dane in the late 1930s. It was soon turned down, because the opening move - a chirogenic Diels-Alder reaction - did not work. With Lewis acids as mediators, however, a successful start has been achieved now. With Ti complexes of chelating ligands (Seebach's TADDOLs (= α,α,α',α'-tetraaryl-1,3-dioxolane-4,5-dimethanols)), enantioselective formation of the desired adducts does occur. Efficient total syntheses of 2 and 3a have been accomplished.
Totally synthetic steroid hormones. 13. The chemical resolution of some racemic estrane, 13-beta-ethylgonane, and 13-beta-n-propylgonane derivatives and the preparation of some estrane and 13-beta-ethylgonane derivatives of unnatural configuration.
Buzby Jr.,Hartley,Hughes,Smith,Gadsby,Jansen
, p. 199 - 204 (2007/10/06)
-
