74440-80-5

Basic information

• Product Name: 4-amino-3-bromophenol
• Synonyms: 4-amino-3-bromophenol
• CAS NO: 74440-80-5
• Molecular Formula: C₆H₆BrNO
• Molecular Weight: 188
• Mol File: 74440-80-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 151 °C
• Boiling Point: 310.7±27.0 °C(Predicted)
• Appearance: /
• Density: 1.768±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 9.26±0.18(Predicted)
• CAS DataBase Reference: 4-amino-3-bromophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-3-bromophenol(74440-80-5)
• EPA Substance Registry System: 4-amino-3-bromophenol(74440-80-5)

Safety Data

• Hazardous Substances Data: 74440-80-5(Hazardous Substances Data)

Usage

General Description

4-Amino-3-bromophenol is a chemical compound with the formula C6H6BrNO. It is a white to light yellow solid at room temperature and is primarily used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is classified as a phenol, containing both a hydroxyl group and an amino group on a benzene ring, as well as a bromine substituent. 4-Amino-3-bromophenol is also used in the production of dyes, pigments, and other colorants due to its ability to form stable and vibrant color complexes. It is important to handle this chemical with caution, as it can be hazardous to human health and the environment if not properly managed.

Upstream product

• 123-30-8 4-amino-phenol 
• 577-19-5 2-nitrophenyl bromide 
• 5470-65-5 3-bromo-4-nitrophenol 

Downstream Products

• 1214890-60-4 C₆H₄Br₃NO 
• 188721-64-4 4-amino-3,5-dibromophenol 

Relevant articles and documents

Polymer-anchored peroxo compounds of molybdenum and tungsten as efficient and versatile catalysts for mild oxidative bromination

A polymer supported peroxomolybdate(VI) compound of the type [MoO 2(O2)(CN)2]-PAN [PAN = poly(acrylonitrile)] (PANMo) was obtained by reacting H2MoO4 with 30% H 2O2 and the macromolecular ligand, PAN at near neutral pH. The macrocomplex has been characterized by elemental analysis (CHN and EDX analysis), spectral (IR, UV-Vis and 13C NMR, 95Mo NMR), thermal (TGA-DTG) as well as SEM studies. The catalytic activity of PANMo and its previously reported tungsten containing analog PANW, in oxidative bromination of organic substrates has been explored. The supported complexes could serve as efficient heterogeneous catalysts for the oxidative bromination of a variety of structurally diverse aromatic compounds, with H 2O2 as terminal oxidant, to afford bromo organics in impressive yields under environmentally clean conditions. The catalysts afforded regeneration and could be reused for a minimum of six reaction cycles.

Heterocycle annulation of enolizable vinyl quinone imides. Dihydroquinolines and quinolines from thermal 6π-electrocyclizations and indoles from photochemical cyclizations

(equation presented) Enolizable vinyl quinone mono-and diimide substrates yield protected 6-hydroxy and 6-amino dihydroquinolines by thermal electrocyclization. Aromatization provides the corresponding quinolines in quantitative yields. The quinone monoimide substrates undergo clean photochemical conversion to 5-hydroxy indoles.