74465-19-3

Basic information

• Product Name: (2R,3S,5S,6S)-2,3,5,6-tetrahydroxycyclohexane-1,4-diyl bis[dihydrogen (phosphate)]
• Synonyms: 1,2,3,4,5,6-cyclohexanehexol, 1,4-bis(dihydrogen phosphate), (2R,3S,5S,6S)-
• CAS NO: 74465-19-3
• Molecular Formula: C₆H₁₄O₁₂P₂
• Molecular Weight: 340.1157
• Mol File: 74465-19-3.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 725.9°C at 760 mmHg
• Flash Point: 392.8°C
• Density: 2.15g/cm³
• Vapor Pressure: 2.49E-24mmHg at 25°C
• Refractive Index: 1.641
• CAS DataBase Reference: (2R,3S,5S,6S)-2,3,5,6-tetrahydroxycyclohexane-1,4-diyl bis[dihydrogen (phosphate)](CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S,5S,6S)-2,3,5,6-tetrahydroxycyclohexane-1,4-diyl bis[dihydrogen (phosphate)](74465-19-3)
• EPA Substance Registry System: (2R,3S,5S,6S)-2,3,5,6-tetrahydroxycyclohexane-1,4-diyl bis[dihydrogen (phosphate)](74465-19-3)

Safety Data

• Hazardous Substances Data: 74465-19-3(Hazardous Substances Data)

Usage

Description

(2R,3S,5S,6S)-2,3,5,6-tetrahydroxycyclohexane-1,4-diyl bis[dihydrogen (phosphate)] is a cyclohexane-based chemical compound featuring a four-carbon cyclohexane ring with four hydroxyl groups at positions 2, 3, 5, and 6 in a specific stereochemical configuration. The molecule also has two phosphate groups attached to carbon atoms 1 and 4, forming dihydrogen phosphate esters. This derivative of cyclohexane exhibits high water solubility and possesses unique structural and property characteristics, making it suitable for a range of chemical and biological applications.

Uses

Used in Chemical Industry:
(2R,3S,5S,6S)-2,3,5,6-tetrahydroxycyclohexane-1,4-diyl bis[dihydrogen (phosphate)] is used as a building block for synthesizing various complex organic molecules and pharmaceutical compounds due to its unique cyclohexane core and reactive hydroxyl and phosphate groups.
Used in Pharmaceutical Industry:
(2R,3S,5S,6S)-2,3,5,6-tetrahydroxycyclohexane-1,4-diyl bis[dihydrogen (phosphate)] is used as a potential therapeutic agent for the development of drugs targeting specific biological pathways and receptors, given its high water solubility and unique structure that can be modified for specific interactions.
Used in Biotechnology Industry:
(2R,3S,5S,6S)-2,3,5,6-tetrahydroxycyclohexane-1,4-diyl bis[dihydrogen (phosphate)] is used as a component in the design of novel biomaterials and drug delivery systems, taking advantage of its water solubility and ability to form stable complexes with other molecules.
Used in Environmental Applications:
(2R,3S,5S,6S)-2,3,5,6-tetrahydroxycyclohexane-1,4-diyl bis[dihydrogen (phosphate)] is used as a component in the development of eco-friendly chemicals and materials, such as biodegradable plastics and water treatment agents, due to its biodegradable nature and potential to form complexes with pollutants.

Upstream product

• 87-89-8 D-myo-inositol 
• 117666-29-2 (+/-)-3,6-di-O-allyl-4-O-benzyl-1,2-O-cyclohexylidene-myo-inositol 
• 112204-05-4 (+/-)-3,6-di-O-allyl-1,2-O-cyclohexylidene-myo-inositol 
• 51548-88-0 (+/-)-1,2:4,5-di-O-isopropylidene-myo-inositol 
• 34361-60-9 1,2:4,5-dicyclohexylidene-myo-inositol 
• 136740-88-0 (+/-)-2,3,6-tri-O-benzyl-myo-inositol 1,4-bis(dibenzyl phosphate) 
• 34361-60-9 1L-1,2:4,5-di-O-cyclohexylidene-myo-inositol 
• 138480-24-7 D-1,4-di-O-tert-butyldimethylsilyl-2,3-O-(D-1,7,7-trimethyl<2.2.1>-bicyclohept-2-ylidene)-myo-inositol 
• 138480-26-9 D-5,6-O-isopropylidene-2,3-O-(D-1,7,7-trimethyl<2.2.1>bicyclohept-2-ylidene)-myo-inositol 
• 128459-27-8 1D-2,3-O-(D-1',7',7'-trimethyl<2.2.1>bicyclohept-2'-ylidene)-myo-inositol 
• 222420-78-2 (1R,2S,3S,4R)-1,4-bis-O-(di-O-benzylphospho)conduritol B 
• 37170-02-8 (+)-2,3:5,6-(1,2:4,5)-dicyclohexylidene-myo-inositol 1,4-(3,6)-bis(diphenylphosphate) 
• 138480-27-0 D-1,4-di-O-(2-oxo-5,6-benzo-1,3,2-dioxaphosphep-2-yl)-2,3-O-(D-1,7,7-trimethyl<2.2.1>bicyclohept-2-ylidene)-5,6-O-isopropylidene-myo-inositol 
• 75194-94-4 3,3,7,7-tetramethyl-2,8-dioxa-5-aza-1λ³-phosphabicyclo(3,3,0)octane 

Relevant articles and documents

A Chiral Phosphoramidite Reagent for the Synthesis of Inositol Phosphates

There is a paucity of chiral phosphoramidite reagents or chiral catalysis methods for the synthesis of biologically relevant inositol phosphates. A new C2-symmetrical chiral phosphoramidite has been developed and successfully applied to the syn

A thiophosphate analog of dimyristoylphosphatidyl-inositol-4-phosphate is a substrate for mammalian phosphoinositide-specific phospholipase C

1,2-Dimyristoyloxypropane-3-thiophosphate(rac-1-myo-inositol-4- phosphate), a thiophosphate analog of dimyristoyl phosphatidylinositol-4- phosphate was synthesized as a substrate for mammalian phosphoinositide- specific phospholipase C. Its activity with A(1-132)-PI-PLC-δ1 (a deletion mutant with the N-terminal pleckstrin homology domain removed) was studied in sonicated dispersions, with and without added Triton X-100. It had an initial activity of about 30 μmol min-1 mg-1, which rapidly decreased due to substrate depletion in the vesicle or micelle. The slower rate of hydrolysis appeared limited by enzyme hopping or exchange of substrate between vesicles or micelles, which was more rapid in the presence of detergent.

The synthesis of homochiral inositol phosphates from myo-inositol

A new synthetic procedure for efficient conversion of myo-inositol into homochiral inositol phosphates is presented, and is illustrated with total synthesis of myo-inositol 1-phosphate, 2-deoxy-myo-inositol 1-phosphate, myo-inositol 3-phosphate, myo-inosi