74528-46-4

Basic information

• Product Name: 2(5H)-Furanone, 5-methyl-4-phenyl-
• Synonyms: 5-methyl-4-phenyl-5H-furan-2-one;5-Methyl-4-phenyl-5H-furan-2-on
• CAS NO: 74528-46-4
• Molecular Formula: C11H10O2
• Molecular Weight: 174.199
• Mol File: 74528-46-4.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 2(5H)-Furanone, 5-methyl-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(5H)-Furanone, 5-methyl-4-phenyl-(74528-46-4)
• EPA Substance Registry System: 2(5H)-Furanone, 5-methyl-4-phenyl-(74528-46-4)

Safety Data

• Hazardous Substances Data: 74528-46-4(Hazardous Substances Data)

Upstream product

• 5703-57-1 3-phenylpent-4-enoic acid 
• 108-86-1 bromobenzene 
• 36781-65-4 pent-3-ynoic acid 
• 1262883-53-3 (+/-)-tert-butyl penta-2,3-dienoate 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 98-80-6 phenylboronic acid 
• 1094064-55-7 ((C₆H₅)3P)AuC₄O₂(CH₃)(H)(H) 
• 2114-00-3 2-bromo-1-phenyl-1-propanone 
• 5650-40-8 2-hydroxypropiophenone 
• 536-74-3 phenylacetylene 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 84735-55-7 2,2-bis(methylthio)-4-phenyl-2,5-dihydrofuran 
• 84735-60-4 2-(methylthio)-4-phenylfuran 
• 13636-88-9 3,3-bis(methylthio)-1-phenylprop-2-en-1-one 

Relevant articles and documents

Catalytic Cross-Coupling of Vinyl Golds with Diazonium Salts under Photoredox and Thermal Conditions

Catalytically generated vinyl gold complexes from tert-butyl allenoates were found to undergo an efficient cross-coupling with arenediazonium salts. The gold(I)-gold(III) redox cycle can be accessed under two different conditions, i.e., visible-light photoredox as well as a thermally induced radical chain pathway. The current C(sp2)-C(sp2) cross-coupling protocol that is catalytic in gold, would make available desirable structural diversity to the traditional cross-coupling chemistry.

Cu(I)-catalyzed oxidative cyclization of alkynyl oxiranes and oxetanes

In the presence of a Cu(I) catalyst and a pyridine oxide, alkynyl oxiranes and oxetanes can be converted into functionalized five- or six-membered α,β-unsaturated lactones or dihydrofuranaldehydes. This new oxidative cyclization is proposed to proceed via an unusual allenyloxypyridinium intermediate.

Butenolide annelation using a manganese(III) oxidation. A synthesis of 4-arylfuran-2(5H)-ones

A general procedure was developed for the annelation of a butenolide to an aromatic ketone that highlighted a manganese(III) oxidation of aromatic ketones. The oxidation of aromatic ketones with manganese(III) acetate in the presence of 2-bromoacetic acid or the Mn(II) salt of this carboxylic acid provided a regioselectively convenient synthesis of 2-(2-bromoacetoxy) ketones. An Arbuzov or Wittig reaction of 2-(2-bromoacetoxy) ketones followed by cyclisation furnished 4-arylfuran-2(5H)-ones in good yield.