74531-82-1 Usage
Functional Groups
Imidazole ring, carboxylic acid, ester, methyl groups
Structure
The molecule consists of an imidazole ring with two methyl groups at the 1st and 5th positions, a carboxylic acid group at the 4th position, and an ethyl ester group attached to the carboxylic acid.
Appearance
It is likely a solid or oily liquid, depending on the conditions.
Solubility
Soluble in organic solvents like ethanol, methanol, and dichloromethane.
Stability
Stable under normal temperature and pressure, but sensitive to strong acids, bases, and oxidizing agents.
Reactivity
Can undergo reactions such as hydrolysis, esterification, and nucleophilic substitution due to the presence of the ester and imidazole functional groups.
Synthesis
It is synthesized by reacting 1H-imidazole-4-carboxylic acid with an excess of ethanol in the presence of an acid catalyst.
Applications
Used in organic synthesis, pharmaceutical research, and as a starting material for the synthesis of other complex molecules.
Medicinal Chemistry
Has potential applications in medicinal chemistry due to its imidazole ring structure, which is found in many bioactive molecules and pharmaceutical drugs.
Precautions
Handle with care, as it may be harmful if inhaled, ingested, or comes into contact with the skin. Use appropriate safety measures and personal protective equipment when handling this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 74531-82-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,5,3 and 1 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 74531-82:
(7*7)+(6*4)+(5*5)+(4*3)+(3*1)+(2*8)+(1*2)=131
131 % 10 = 1
So 74531-82-1 is a valid CAS Registry Number.
74531-82-1Relevant articles and documents
INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS
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Page/Page column 244; 245, (2021/01/29)
The present invention is directed to indazole and azaindazole compounds which are inhibitors of LRRK2 and are useful in the treatment of CNS disorders.
AMINO-INDOLYL-SUBSTITUTED IMIDAZOLYL-PYRIMIDINES AND THEIR USE AS MEDICAMENTS
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Page/Page column 48, (2013/11/05)
The invention relates to new amino-indole-substituted imidazolyl-pyrimidines of formula (1), wherein R1, R2, R3, R4 and R5 are defined as in claim 1 and pharmaceutically acceptable salts thereof and the use of these compounds for the preparation of a medicament for treating a disease selected from asthma, COPD, rheumatoid arthritis, specific lymphomas and specific diseases of the nervous system
Novel farnesyl protein transferase inhibitors as antitumor agents
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Page 467-468, (2010/02/07)
Disclosed are novel tricyclic compounds represented by the formula (1.0): and a pharmaceutically acceptable salt or solvate thereof. The compounds are useful for inhibiting farnesyl protein transferase. Also disclosed are pharmaceutical compositions comprising compounds of formula 1.0. Also disclosed are methods of treating cancer using the compounds of formula 1.0.