745829-36-1

Basic information

• Product Name: 7-methylthio-1,2-benzisothiazole-3-one-1,1-dioxide
• Synonyms: 7-methylthio-1,2-benzisothiazole-3-one-1,1-dioxide
• CAS NO: 745829-36-1
• Molecular Weight: 229.28
• Mol File: 745829-36-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-methylthio-1,2-benzisothiazole-3-one-1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methylthio-1,2-benzisothiazole-3-one-1,1-dioxide(745829-36-1)
• EPA Substance Registry System: 7-methylthio-1,2-benzisothiazole-3-one-1,1-dioxide(745829-36-1)

Safety Data

• Hazardous Substances Data: 745829-36-1(Hazardous Substances Data)

Upstream product

• 77820-58-7 methyl 3-chloroanthranilate 

Relevant articles and documents

Facile synthesis of 1, 2-benzisothiazole-3-one-1,1-dioxide methylsulfonyl derivatives

An improved and general synthesis of saccharin methylthio and methylsulfone derivatives from chloro-substituted saccharins is presented. A large-scale procedure for preparation of chloro-substituted saccharins was developed. Treatment of the saccharin chlorides with sodium thiomethoxide and t-BuOK in DMF gave the saccharin methyl sulfides, which upon chromium(VI) oxide catalyzed oxidation with periodic acid afforded the corresponding saccharin methylsulfones in high yields.