74590-71-9

Basic information

• Product Name: 2-fluoro-2-(2,4,5-trichlorophenoxy)acetic acid
• Synonyms: 2-fluoro-2-(2,4,5-trichlorophenoxy)acetic acid
• CAS NO: 74590-71-9
• Molecular Weight: 273.475
• Mol File: 74590-71-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-fluoro-2-(2,4,5-trichlorophenoxy)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-fluoro-2-(2,4,5-trichlorophenoxy)acetic acid(74590-71-9)
• EPA Substance Registry System: 2-fluoro-2-(2,4,5-trichlorophenoxy)acetic acid(74590-71-9)

Safety Data

• Hazardous Substances Data: 74590-71-9(Hazardous Substances Data)

Upstream product

• 359-25-1 bromo-fluoroacetic acid 
• 95-95-4 2,4,5-trichlorophenol 
• 373-91-1 hypofluorous acid trifluoromethyl ester 
• 93-76-5 2,4,5-Trichlorophenoxyacetic acid 
• 75580-98-2 1-(2,2-Bis-trimethylsilanyloxy-vinyloxy)-2,4,5-trichloro-benzene 

Relevant articles and documents

Herbicidal and fungistatic properties of fluorine analogs of phenoxyacetic herbicides

Aryloxy fluoroacetic acids 3a-3h – fluorine analogs of phenoxyacetic herbicides 2,4-D, MCPA, 2,4,5-T, and 4-CPA were efficiently synthesized in 29–88% yield, using appropriate phenols and either bromodifluoro- or bromofluoroacetic acid in the presence of sodium hydride as a base and in either dioxane or THF as solvents. Fluorine derivatives of 2,4-D (3a, 3b) show herbicidal activity against three weed species. Parent herbicides 2,4-D, MCPA, 2,4,5-T, 4-CPA, monofluorine derivatives of MCPA (3d) and 2,4,5-T (3f) show fungistatic activity against phytopatogenic fungi species Phytophtora cactorum.

Synthesis of α-fluorocarbonyl compounds

Process for preparing an organic compound of the formula R2 R2 CFC(O)R3, which process comprises contacting and reacting in a reaction mixture which includes an inert solvent, at a temperature of -40° C. to -100° C., ROF and STR1 R is polyfluoroperhaloalkyl of 1-6 carbon atoms or FOCF2 ; R1 is hydrocarbyl of 1-6 carbon atoms; each R2 is selected from H, alkyl of 1-17 carbon atoms, cycloalkyl of 3-6 carbon atoms, aryl, heteroaryl and such alkyl, cycloalkyl, aryl and heteroaryl substituted by halogen or alkoxy of 1-6 carbon atoms; R3 is selected from H, alkyl and haloalkyl of 1-16 carbon atoms, cycloalkyl of 3-10 carbon atoms, aryl and haloaryl, OSi(R1)3, OH, NH2, alkoxy of 1-6 carbon atoms, aryloxy, NHR1 and NR12 wherein R1 is alkyl of 1-6 carbon atoms, N-arylamino and nitrogen or sulfur heterocyclic of 4-5 carbon atoms; R3 and one R2 taken together is a diradical which with the C=C group is carbocyclic, heterocyclic or haloheterocyclic, and recovering from the reaction mixture the compound of the formula R2 R2 CFC(O)R3.