7462-79-5

Basic information

• Product Name: 1-(biphenyl-4-yl)-2-hydroxypropan-1-one
• CAS NO: 7462-79-5
• Molecular Formula: C₁₅H₁₄O₂
• Molecular Weight: 226.2705
• Mol File: 7462-79-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 381.6°C at 760 mmHg
• Flash Point: 163°C
• Density: 1.127g/cm³
• Vapor Pressure: 1.66E-06mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: 1-(biphenyl-4-yl)-2-hydroxypropan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(biphenyl-4-yl)-2-hydroxypropan-1-one(7462-79-5)
• EPA Substance Registry System: 1-(biphenyl-4-yl)-2-hydroxypropan-1-one(7462-79-5)

Safety Data

• Hazardous Substances Data: 7462-79-5(Hazardous Substances Data)

Usage

Appearance

White solid

Odor

Slightly sweet, floral

Uses

a. Production of fragrances and flavorings
b. Intermediate in the synthesis of pharmaceuticals and other organic compounds

Chemical classification

Derivative of acetophenone

Properties

a. Antioxidant
b. Anti-inflammatory

Potential applications

a. Material science
b. Production of polymers and other high-performance materials

Upstream product

• 73932-60-2 α-chloro-4-phenylpropiophenone 

Downstream Products

• 129159-23-5 biphenyl-4-yl 1-fluoroethyl ketone 

Relevant articles and documents

Photochemical Rearrangement of α-Chloro-Propiophenones to α-Arylpropanoic Acids: Studies on Chirality Transfer and Synthesis of (S)-(+)-Ibuprofen and (S)-(+)-Ketoprofen

A new single-step efficient photochemical approach for α-arylpropanoic acids (4) from α-chloro-propiophenones (5) is described.It involves carbonyl triplet excited state directed 1,2-aryl migration of the aryl group which has been found to be highly dependent upon the nature of the aryl substituent.The mode of the rearrangement is probed by the study of the photobehaviour of a set of optically active α-chloro-propiophenones.The results suggest that the nature of the carbonyl triplets (n, ?*/ ?, ?*) plays an important role in the chirality transfer.This method finds application in the synthesis of optically active ibuprofen (4e) and ketoprofen (26), though in moderate optical yields.