74630-73-2

Basic information

• Product Name: 6-PHENYLIMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE
• Synonyms: 6-PHENYL-IMIDAZO[2,1-B]THIAZOLE-5-CARBALDEHYDE;6-PHENYLIMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE;IMIDAZO[2,1-B]THIAZOLE-5-CARBOXALDEHYDE, 6-PHENYL-;IFLAB-BB F1996-0024;AURORA KA-4217;BUTTPARK 2\01-49;6-phenyl-5-imidazo[2,3-b]thiazolecarboxaldehyde;6-phenylimidazo[2,3-b][1,3]thiazole-5-carbaldehyde
• CAS NO: 74630-73-2
• Molecular Formula: C₁₂H₈N₂OS
• Molecular Weight: 228.27
• Mol File: 74630-73-2.mol
• Article Data: 8

Chemical Properties

• Melting Point: 130-132°C
• Appearance: /
• Density: 1.36g/cm³
• Refractive Index: 1.715
• CAS DataBase Reference: 6-PHENYLIMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-PHENYLIMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE(74630-73-2)
• EPA Substance Registry System: 6-PHENYLIMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE(74630-73-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 74630-73-2(Hazardous Substances Data)

Usage

General Description

6-PHENYLIMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE is a chemical compound with a complex and specific molecular structure that consists of a phenyl group attached to an imidazo-thiazole ring. It is classified as a carbonyl compound due to the presence of a carbonyl (aldehyde) functional group in its molecular structure. This chemical may have various applications in organic synthesis, medicinal chemistry, or material science due to its unique structure and potential reactivity. It may also possess biological activity that could be of interest for pharmaceutical research and drug development. However, the exact properties and uses of 6-PHENYLIMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE would depend on further research and investigation.

InChI:InChI=1/C12H8N2OS/c15-8-10-11(9-4-2-1-3-5-9)13-12-14(10)6-7-16-12/h1-8H

Upstream product

• 70-11-1 α-bromoacetophenone 
• 51226-38-1 5-methyl-6-phenylimidazo[2,1-b]thiazole 
• 7008-63-1 6-phenylimidazo[2,1-b]thiazole 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 76919-46-5 Acetic acid 6-phenyl-imidazo[2,1-b]thiazol-5-ylmethyl ester 
• 76919-58-9 Ethyl-carbamic acid 6-phenyl-imidazo[2,1-b]thiazol-5-ylmethyl ester 
• 723341-43-3 N-{4-[(E)-2-(6-phenylimidazo[2,1-b][1,3]thiazol-5-yl)vinyl]pyrimidin-2-yl}acetamide 
• 723341-67-1 N-phenyl-4-[(E)-2-(6-phenylimidazo[2,1-b][1,3]thiazol-5-yl)vinyl]pyrimidin-2-amine 
• 723341-66-0 N-(1-phenylethyl)-4-[(E)-2-(6-phenylimidazo[2,1-b][1,3]thiazol-5-yl)vinyl]pyrimidin-2-amine 

Relevant articles and documents

Synthesis, crystal structure, antimicrobial activity and docking studies of new imidazothiazole derivatives

A series of imidazothiazole derivatives were synthesized via Claisen–Schmidt condensation of aldehyde 3, and different methyl ketones and their chemical structures were confirmed using 13C NMR, 1H NMR and LC–MS. In addition, the mole

DL5050, a Selective Agonist for the Human Constitutive Androstane Receptor

The constitutive androstane receptor (CAR) is a xenobiotic sensor governing the transcription of genes involved in drug disposition, energy homeostasis, and cell proliferation. However, currently available human CAR (hCAR) agonists are nonselective, which

Synthesis of new triazole fused imidazo[2,1-b]thiazole hybrids with emphasis on Staphylococcus aureus virulence factors

A series of new triazole fused imidazo[2,1-b]thiazole hybrids (9a–u) were designed, synthesized and evaluated as antimicrobial agents. Compounds 9c, 9d, 9e, 9j and 9l showed promising broad spectrum antimicrobial activity. Further, compound 9c exhibited s