7466-26-4

Basic information

• Product Name: (E)-1-(4-bromophenyl)-2-(4-chlorophenyl)diazene
• CAS NO: 7466-26-4
• Molecular Formula: C₁₂H₈BrClN₂
• Molecular Weight: 295.5623
• Mol File: 7466-26-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 391.1°C at 760 mmHg
• Flash Point: 190.3°C
• Density: 1.47g/cm³
• Vapor Pressure: 5.7E-06mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: (E)-1-(4-bromophenyl)-2-(4-chlorophenyl)diazene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(4-bromophenyl)-2-(4-chlorophenyl)diazene(7466-26-4)
• EPA Substance Registry System: (E)-1-(4-bromophenyl)-2-(4-chlorophenyl)diazene(7466-26-4)

Safety Data

• Hazardous Substances Data: 7466-26-4(Hazardous Substances Data)

Usage

Description

(E)-1-(4-bromophenyl)-2-(4-chlorophenyl)diazene is a chemical compound characterized by its molecular formula C12H8BrClN. It is a diazene compound featuring both bromo and chloro substituted phenyl groups. This yellow to brown solid is insoluble in water but readily soluble in organic solvents. Its unique structure and properties make it a versatile compound with potential applications in various fields.

Uses

Used in Organic Synthesis:
(E)-1-(4-bromophenyl)-2-(4-chlorophenyl)diazene is used as a building block in the synthesis of other chemical compounds. Its reactivity and structural features make it a valuable component in creating a diverse range of molecules with specific properties and functions.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (E)-1-(4-bromophenyl)-2-(4-chlorophenyl)diazene is utilized as a key intermediate in the development of new drugs. Its potential role in drug discovery is attributed to its unique chemical properties, which can be harnessed to create novel therapeutic agents.
Used in Medical Imaging:
(E)-1-(4-bromophenyl)-2-(4-chlorophenyl)diazene has been studied for its potential use in medical imaging. Its properties may allow for the development of new imaging agents that can enhance the visualization and detection of various medical conditions.
Used in Anticancer Research:
Although further research is required, (E)-1-(4-bromophenyl)-2-(4-chlorophenyl)diazene has shown promise as a potential anticancer agent. Its unique structure and reactivity may contribute to the development of new treatments for cancer, offering new avenues for therapeutic intervention.

Upstream product

• 106-47-8 4-chloro-aniline 
• 106-40-1 4-bromo-aniline 
• 108-95-2 phenol 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 3035-94-7 4-((p-bromophenyl)diazenyl)phenol 
• 4340-77-6 4-chloroazobenzene 
• 932-98-9 1-chloro-4-nitroso-benzene 

Relevant articles and documents

Aromatic amine oxidation process for preparing aromatic azobenzene method

The invention relates to a method for preparing an aromatic azo compound by utilizing aromatic amine oxidation. In the method, air or oxygen serves as an oxygen source, and under the effect of a catalyst, aromatic amine is oxidized into the aromatic azo compound. The method is high in oxidization efficiency and product yield; the air or the oxygen serves as the oxygen source, and the method is economical and environmentally friendly. The product and the catalyst can be separated easily, and the aftertreatment is simple. The catalyst is easy to reuse, and the method has very good application prospect.

Phenyliodine(III) diacetate (PIDA) mediated synthesis of aromatic azo compounds through oxidative dehydrogenative coupling of anilines: Scope and mechanism

An efficient and environmentally benign method has been developed for the synthesis of symmetrical and unsymmetrical aromatic azo compounds through phenyliodine(III) diacetate (PIDA) mediated oxidative dehydrogenative coupling of anilines in high yields.

Highly efficient synthesis of azos catalyzed by the common metal copper (0) through oxidative coupling reactions

A facile and efficient approach to synthesize symmetric, asymmetric and bridged aromatic azo compounds (AAzos) from aromatic amines was developed by using red copper as catalyst. Despite numerous efforts towards the catalytic synthesis of symmetric and asymmetric AAzos derivatives, most reactions present certain drawbacks inhibiting their industrial applications, such as laborious multi-step processes, harsh reaction conditions and expensive reagents. And the synthesis of bridged azos had low yields before. With the presence of ammonium bromide as co-catalyst, pyridine as a ligand and molecular dioxygen as a sole oxidative reagent, red copper, a common and abundant metal in nature, exhibited unexpected catalytic activity towards the preparation of AAzos in high yields via one-step reaction, making this catalyst an attractive candidate for industrial and synthetic applications.