746630-34-2

Basic information

• Product Name: 1-(4-BroMo-2,6-difluoro-phenyl)-ethanone
• Synonyms: 1-(4-BroMo-2,6-difluoro-phenyl)-ethanone;4'-bromo-2',6'-difluoroacetophenone
• CAS NO: 746630-34-2
• Molecular Formula: C₈H₅BrF₂O
• Molecular Weight: 235.0255064
• Mol File: 746630-34-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 246.1±40.0 °C(Predicted)
• Appearance: /
• Density: 1.614±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-(4-BroMo-2,6-difluoro-phenyl)-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-BroMo-2,6-difluoro-phenyl)-ethanone(746630-34-2)
• EPA Substance Registry System: 1-(4-BroMo-2,6-difluoro-phenyl)-ethanone(746630-34-2)

Safety Data

• Hazardous Substances Data: 746630-34-2(Hazardous Substances Data)

Usage

General Description

1-(4-Bromo-2,6-difluoro-phenyl)-ethanone is a chemical compound characterized by the arrangement of halogens, bromine and fluorine, on a phenyl group connected to an ethanone group. Its molecular formula is C8H5BrF2O, indicating it contains eight carbon atoms, five hydrogen atoms, one bromine atom, two fluorine atoms, and one oxygen atom. Listed in certain chemical supplier databases, its potential usage could vary across different industries or in scientific research, though specific application details might be underreported in openly available literature. 1-(4-BroMo-2,6-difluoro-phenyl)-ethanone is not widely discussed so its physical and chemical properties along with toxicity and safety measures associated with its use may need to be determined experimentally or inquired directly from relevant manufacturers.

Upstream product

• 184910-20-1 (4-bromo-2,6-difluoro-phenyl)-trimethyl-silane 
• 75-36-5 acetyl chloride 
• 183065-68-1 4-bromo-2,6-difluorobenzoic acid 
• 75-16-1 methylmagnesium bromide 
• 461-96-1 3,5-difluorobromobenzene 
• 108-24-7 acetic anhydride 

Downstream Products

• 746630-35-3 2-bromo-1-(4-bromo-2,6-difluorophenyl)ethan-1-one 

Relevant articles and documents

P2X3 MODULATORS

Provided herein are P2X3 modulators and methods of utilizing P2X3 modulators in the treatment of diseases, disorders, or conditions. Also described herein are pharmaceutical compositions containing such compounds.

BIARYL DERIVATIVE AS GPR120 AGONIST

The present invention relates to a biaryl derivative expressed by the chemical formula 1, a method for producing the biaryl derivative, a pharmaceutical composition comprising same, and use of same, the biaryl derivative expressed by the chemical formula 1, as a GPR120 agonist, promoting GLP-1 generation in the gastro-intestinal tract, reducing insulin resistance in the liver, muscles and the like from anti-inflammatory activity in the macrophage, pancreatic cells and the like, and allowing effective use in prevention or treatment of inflammation or metabolic diseases such as diabetes, complications from diabetes, obesity, non-alcoholic fatty liver disease, fatty liver disease, and osteoporosis.

PYRAZOLYL-SUBSTITUTED HETEROARYLS AND THEIR USE AS MEDICAMENTS

The invention relates to new substituted heteroaryls of formula 1 or of formula 1' wherein A is either N or CH, wherein R2 is selected from the group consisting of -C1-3-alkyl, -C1-3-haloalkyl, F, Br, CI, wherein Y is selected from -O- or -CH2-, and wherein R3 is defined as in claim 1, and the pharmaceutically acceptable salts thereof, and the use of these aforementioned compounds for the treatment of diseases such as asthma, COPD, allergic rhinitis, allergic dermatitis, lupus erythematodes, lupus nephritis and rheumatoid arthritis.