7467-78-9

Basic information

• Product Name: 3,4-Diphenylisoxazole
• Synonyms: 3,4-Diphenylisoxazole
• CAS NO: 7467-78-9
• Molecular Formula: C₁₅H₁₁NO
• Molecular Weight: 221.2539
• Mol File: 7467-78-9.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 353.2°Cat760mmHg
• Flash Point: 126.8°C
• Appearance: /
• Density: 1.128g/cm³
• Vapor Pressure: 7.4E-05mmHg at 25°C
• Refractive Index: 1.586
• CAS DataBase Reference: 3,4-Diphenylisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Diphenylisoxazole(7467-78-9)
• EPA Substance Registry System: 3,4-Diphenylisoxazole(7467-78-9)

Safety Data

• Hazardous Substances Data: 7467-78-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H11NO/c1-3-7-12(8-4-1)14-11-17-16-15(14)13-9-5-2-6-10-13/h1-11H

Upstream product

• 19881-68-6 (Z)-β-chloro-α,β-diphenylacrolein 
• 1451998-23-4 tert-butyl 3-methoxy-3-phenylazetidine-1-carboxylate 
• 100-58-3 phenylmagnesium bromide 
• 536-74-3 phenylacetylene 
• 932-90-1 Benzaldoxime 
• 119072-55-8 tert-butylisonitrile 
• 501-65-5 diphenyl acetylene 
• 866625-51-6 2,3-diphenyl-2H-azirine-2-carbaldehyde 
• 574-15-2 (E)-benzil monooxime 
• 28884-09-5 phenyl-(2-phenyl-oxiranyl)-methanone oxime 
• 859810-09-6 2-bromo-1-(4-methoxy-phenyl)-4-nitro-3,4-diphenyl-butan-1-one 
• 859810-12-1 2-bromo-1-(4-chloro-phenyl)-4-nitro-3,4-diphenyl-butan-1-one 
• 934-16-7 phenylhydroxamoyl chloride 
• 37630-43-6 (Z)-1-(methylsulfonyl)-2-phenylethene 

Downstream Products

• 574-15-2 (E)-benzil monooxime 
• 574-16-3 (Z)-benzilmonooxime 
• 64545-16-0 2-phenyl-2-(trimethylsilyl)ethenone 

Relevant articles and documents

Chemodivergent and Stereoselective Access to Fused Isoxazoline Azetidines and Thietanes through [3 + 2]-Cycloadditions

By combining efficient methodologies for the preparation of substituted azetines and thietes with a highly regio- and diastereoselective [3 + 2]-cycloaddition, a straightforward pathway for the synthesis of fused isoxazoline azetidines and thietanes has been designed. With minimal steps and starting from commercial sources, a new library of elaborated architectures was synthesized opening up a new class of molecules with large potential in pharmacology. Finally, a retro [2 + 2]-cycloaddition leading to substituted isoxazoles is described.

Regioselective conversion of alkynes to 4-substituted and 3,4-disubstituted isoxazoles using titanium-catalyzed multicomponent coupling reactions

Conditions have been developed for the regioselective synthesis of 4-substituted isoxazoles from terminal alkynes and 3,4-disubstituted isoxazoles from internal alkynes. The methodology involves a one-pot titanium-catalyzed multicomponent coupling reactio

One-pot copper(I)-catalyzed synthesis of 3,5-disubstituted isoxazoles

3,5-Disubstituted isoxazoles are obtained in good yields by a convenient one-pot, three-step procedure utilizing a regioselective copper(I)-catalyzed cycloaddition reaction between in situ generated nitrile oxides and terminal acetylenes. Most functional