7471-32-1

Basic information

• Product Name: (1E)-N-hydroxy-1-(3-nitrophenyl)ethanimine
• Synonyms: ethanone, 1-(3-nitrophenyl)-, oxime, (1E)-
• CAS NO: 7471-32-1
• Molecular Formula: C₈H₈N₂O₃
• Molecular Weight: 180.1607
• Mol File: 7471-32-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 334.546°C at 760 mmHg
• Flash Point: 156.128°C
• Density: 1.293g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.578
• CAS DataBase Reference: (1E)-N-hydroxy-1-(3-nitrophenyl)ethanimine(CAS DataBase Reference)
• NIST Chemistry Reference: (1E)-N-hydroxy-1-(3-nitrophenyl)ethanimine(7471-32-1)
• EPA Substance Registry System: (1E)-N-hydroxy-1-(3-nitrophenyl)ethanimine(7471-32-1)

Safety Data

• Hazardous Substances Data: 7471-32-1(Hazardous Substances Data)

Usage

General Description

(1E)-N-hydroxy-1-(3-nitrophenyl)ethanimine is a compound with the chemical formula C8H8N2O3. It belongs to the class of organic compounds known as acetamidines. (1E)-N-hydroxy-1-(3-nitrophenyl)ethanimine is a brown powder with a molecular weight of 188.16 g/mol. It is not soluble in water but is soluble in organic solvents. The (1E)-N-hydroxy-1-(3-nitrophenyl)ethanimine compound has potential applications in pharmaceuticals and in the synthesis of other organic compounds. It is important to handle and use this compound with care, as it may have potential health hazards and must be handled in a well-ventilated area with appropriate protective gear.

Upstream product

• 99-61-6 3-nitro-benzaldehyde 
• 107093-05-0 1-Hydroxyamino-1-(3-nitro-phenyl)-ethanol 
• 586-39-0 1-nitro-3-vinyl-benzene 
• 121-89-1 3-Nitroacetophenone 

Downstream Products

• 6303-59-9 (E)-4-(2-bromo-vinyl)-anisole 
• 21115-69-5 N-(3-nitrophenyl)ethanethioamide 
• 13651-07-5 2,2-dibromo-1-(3-nitrophenyl)ethan-1-one 
• 90271-37-7 3-nitro-α-methylbenzylamine 
• 129725-48-0 α-(3-aminophenyl)ethylamine 

Relevant articles and documents

Copper(0)/PPh3-Mediated Bisheteroannulations of o-Nitroalkynes with Methylketoximes Accessing Pyrazo-Fused Pseudoindoxyls

A copper(0)/PPh3-mediated cascade bisheteroannulation reaction of o-nitroalkynes with methylketoximes has been developed that provides viable access to a diverse range of pyrazo-fused pseudoindoxyl compounds. Synthetically useful functional groups including sensitive C-I bonds are compatible with this system. Mechanistic studies suggest a reaction cascade involving sequential PPh3-mediated deoxygenative cycloisomerization and copper-catalyzed [3 + 2] pyrazo-annulation.

SO2F2-Activated Efficient Beckmann Rearrangement of Ketoximes for Accessing Amides and Lactams

A novel, mild and practical protocol for the efficient activation of the Beckmann rearrangement utilizing the readily available and economical sulfuryl fluoride (SO2F2 gas) has been developed. The substrate scope of the operationally simple methodology has been demonstrated by 37 examples with good to nearly quantitative isolated yields (over 90 % yield in most cases) in a short time, including B(OH)2, COOH, NH2, and OH substituted substrates. A tentative mechanism was proposed involving formation and elimination of key intermediate, sulfonyl ester.

TETRAZOLINONE COMPOUND AND USE THEREOF

The compound represented by formula (1): wherein R4 and R5 each represents a hydrogen atom, a halogen atom, or a C1-C3 alkyl group; R6 represents a C1-C4 alkyl group, a C3-C6 cycloalkyl group, or the like; R7, R8, and R9 each represents a hydrogen atom, a halogen atom, or the like; R10 represents a C1-C3 alkyl group, or the like; R13 represents a C1-C3 alkyl group, or the like; and Q represents a phenyl group, or the like; has an excellent control effect on pests.