74764-17-3 Usage
Description
N-2-Pyridinyl-1,2-ethanediamine is an organic compound that serves as a key reactant in the synthesis of various pharmaceutical agents. It is characterized by its pyridine ring and two ethylenediamine groups, which contribute to its reactivity and potential applications in medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
N-2-Pyridinyl-1,2-ethanediamine is used as a reactant for the synthesis of dual histamine H1 and H2 receptor antagonists based on cyanoguanidine. These antagonists are important in the development of medications that target histamine receptors, which play a crucial role in allergic reactions and other inflammatory processes.
Additionally, N-2-Pyridinyl-1,2-ethanediamine is used in the synthesis of 2-thiohydantoins as somatostatin receptor ligands. Somatostatin receptor ligands have potential applications in the treatment of various conditions, including neuroendocrine tumors and diabetes, by modulating the activity of somatostatin receptors.
Check Digit Verification of cas no
The CAS Registry Mumber 74764-17-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,7,6 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 74764-17:
(7*7)+(6*4)+(5*7)+(4*6)+(3*4)+(2*1)+(1*7)=153
153 % 10 = 3
So 74764-17-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H11N3/c8-4-6-10-7-3-1-2-5-9-7/h1-3,5H,4,6,8H2,(H,9,10)
74764-17-3Relevant articles and documents
INDOLE AHR INHIBITORS AND USES THEREOF
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Paragraph 00338, (2020/05/21)
The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.
Isoflavone amide type derivative, preparation method and medical application thereof
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Paragraph 0016; 0077; 0078; 0079, (2016/10/10)
The invention relates to the field of medicinal chemistry, and relates to an isoflavone amide type derivative, a preparation method and a medical application thereof, in particular to an isoflavone amide type derivative with the general formula (I), a preparation method thereof, medicine compositions including the isoflavone amide type derivative and a medical application thereof, especially an application of the isoflavone amide type derivative as a medicine for preventing or curing hyperlipemia, obesity or type II diabetes. The general formula (I) is shown in the description.
Synthesis of selectively mono-N-arylated aliphatic diamines via iridium-catalyzed amine alkylation
Blank, Benoit,Michlik, Stefan,Kempe, Rhett
experimental part, p. 2903 - 2911 (2010/03/25)
A highly selective phosphorus/nitrogen (P,N) ligand-based iridium catalyst system efficiently catalyzes the reaction of arylamines with unprotected amino alcohols, yielding N-arylated aliphatic diamines in yields of up to 93%. The reaction can be performe
