74786-70-2

Basic information

• Product Name: 2-isopropylidenemethyl-5-nitrothiophene
• Synonyms: 2-isopropylidenemethyl-5-nitrothiophene
• CAS NO: 74786-70-2
• Molecular Weight: 183.231
• Mol File: 74786-70-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-isopropylidenemethyl-5-nitrothiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-isopropylidenemethyl-5-nitrothiophene(74786-70-2)
• EPA Substance Registry System: 2-isopropylidenemethyl-5-nitrothiophene(74786-70-2)

Safety Data

• Hazardous Substances Data: 74786-70-2(Hazardous Substances Data)

Upstream product

• 20898-86-6 2-(chloromethyl)-5-nitrothiophene 
• 147225-22-7 2-lithio-2-nitropropane 

Relevant articles and documents

New 2-alkylidenemethyl-5-nitrothiophenes: Preparation vis S(RN)1 reactions and in vitro antiprotozoan activity

The reaction of 2-chloromethyl-5-nitrothiophene with the 2-nitropropane anion has been reinvestigated and extended to various nitronate anions to afford good yields of new 5-nitrothiophenes bearing a trisubstituted ethylenic double bond at the 2-position. These compounds were evaluated as potential antiprotozoan agents and some derivatives were found to have the same activity as that of reference compounds.