74819-18-4Relevant articles and documents
Heterocyclic derivative and pharmaceutical composition comprising the same
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, (2016/01/10)
The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic effect. A pharmaceutical composition having a P2X3 and/or P2X2/3 receptor antagonistic effect comprising a compoun
Reactivity of 4-Arylmethyl-3-chloro-6-methylpyridazines Towards Some Nucleophilic Reagents
Ismail, M. F.,Shams, N. A.,Soliman, E. A.,El-Sawy, O. M.
, p. 78 - 79 (2007/10/02)
4-Arylmethyl-3-chloro-6-methylpyridazines (1) react with aniline and hydrazine hydrate to give 3-anilino-(2a-c)- and 3-hydrazino-(2d-f)-pyridazine derivatives, respectively.Sodium azide reacts with 1 to give the tetrazolopyridazines (4).Condensation of (1a,b) with benzaldehyde yields only 4-arylmethyl-6-methylpyridazin-3(2H)-ones (6).