74826-50-9

Basic information

• Product Name: t-butyl(E)-5-oxo-2,5-dihydrofuran-2-ylideneacetate
• Synonyms: t-butyl(E)-5-oxo-2,5-dihydrofuran-2-ylideneacetate
• CAS NO: 74826-50-9
• Molecular Weight: 196.203
• Mol File: 74826-50-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: t-butyl(E)-5-oxo-2,5-dihydrofuran-2-ylideneacetate(CAS DataBase Reference)
• NIST Chemistry Reference: t-butyl(E)-5-oxo-2,5-dihydrofuran-2-ylideneacetate(74826-50-9)
• EPA Substance Registry System: t-butyl(E)-5-oxo-2,5-dihydrofuran-2-ylideneacetate(74826-50-9)

Safety Data

• Hazardous Substances Data: 74826-50-9(Hazardous Substances Data)

Upstream product

• 6118-51-0 exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride 
• 86302-43-4 (tert-Butoxycarbonylmethylene)triphenylphosphorane 

Downstream Products

• 3374-46-7 (Z)-5-oxo-2,5-dihydrofuran-2-ylideneacetic acid 
• 3374-46-7 (2E)-2-(5-oxo-2(5H)-furanylidene)acetic acid 

Relevant articles and documents

The Synthesis of 5-Oxo-2,5-dihydrofuran-2-ylideneacetic Acids

The 5-oxo-2,5-dihydrofuran-2-ylideneacetic acids (2a), (3a), (9a), (10a), (11a), (12a) and (13a) have been synthesized by a procedure which allows the unambiguous assignment of the stereochemistry about the double bond in each isomer.The method, of general application, enables the acids to be prepared from the corresponding t-butyl esters with acid without isomerization about the double bond.The t-butyl esters are available from the Wittig reaction between anhydrides and t-butoxycarbonylmethylenetriphenylphosphorane.Where mainly one isomer is produced in the Wittig reaction, isomerization to an easily separable mixture of the esters can be achieved.Aspects of the isomerization of enol-lactone esters (e.g.(2b)) are descibed