74834-46-1

Basic information

• Product Name: (4-Bromophenyl)(2-thioxo-3-thiazolidinyl)methanone
• Synonyms: (4-Bromophenyl)(2-thioxo-3-thiazolidinyl)methanone;3-(4-Bromobenzoyl)-2-thiazolidinethione;(4-Bromo-phenyl)-(2-thioxo-thiazolidin-3-yl)-methanone
• CAS NO: 74834-46-1
• Molecular Formula: C₁₀H₈BrNOS₂
• Molecular Weight: 302.21062
• Product Categories: chemical additive;pharmaceutical intermediate
• Mol File: 74834-46-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 119-120℃
• Appearance: /
• Density: 1.74
• CAS DataBase Reference: (4-Bromophenyl)(2-thioxo-3-thiazolidinyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Bromophenyl)(2-thioxo-3-thiazolidinyl)methanone(74834-46-1)
• EPA Substance Registry System: (4-Bromophenyl)(2-thioxo-3-thiazolidinyl)methanone(74834-46-1)

Safety Data

• Hazardous Substances Data: 74834-46-1(Hazardous Substances Data)

Usage

Uses

thiazolidin e thione pharmaceutical intermediate

Upstream product

• 134469-06-0 thiazolidine-2-thione 
• 586-75-4 4-chlorobenzoyl chloride 
• 72398-40-4 4-bromobenzoyl fluoride 
• 586-76-5 4-Bromobenzoic acid 
• 63987-96-2 thallium salt of Δ²-1,3-thiazoline-2-thiol 

Relevant articles and documents

3-(P-BROMOBENZOYL)-1,3-THIAZOLIDINE-2-THIONE

C10H8BrNOS2, orthorombic, Pbca, a = 7.166 (4), b = 14.716 (9), c = 21.507 (12) Angstroem (λ = 1.5418 Angstroem), U = 2268 Angstroem3, Z = 8, Dx = 1.77 Mg m-3 = Dm (flotation in C2H5I/toluene), F(000) = 1200, μ(C

Utilisation of Sulphur-containing Leaving Groups. Part 2. Monitored Reduction of Carboxylic Acids into Alcohols or Aldehydes via 3-Acylthiazolidine-2-thiones by Sodium Borohydride or Di-isobutylaluminium Hydride

3-Acylthiazolidine-2-thiones (2) have been prepared by three methods, and treated with di-isobutylaluminium hydride or sodium borohydride to give aldehyde or alcohol in high yield, respectively.The original yellow colour disappears when reduction is finished, enabling the reaction to be monitored.The high reactivity of the carbonyl group in amide (2) was briefly discussed.