748770-65-2

Basic information

• Product Name: 5-Hexyn-1-ol, 6-(2-methylphenyl)-
• CAS NO: 748770-65-2
• Molecular Formula: C13H16O
• Molecular Weight: 188.269
• Mol File: 748770-65-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-Hexyn-1-ol, 6-(2-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hexyn-1-ol, 6-(2-methylphenyl)-(748770-65-2)
• EPA Substance Registry System: 5-Hexyn-1-ol, 6-(2-methylphenyl)-(748770-65-2)

Safety Data

• Hazardous Substances Data: 748770-65-2(Hazardous Substances Data)

Upstream product

• 615-37-2 ortho-methylphenyl iodide 
• 928-90-5 5-hexyl-1-ol 

Downstream Products

• 823785-35-9 6-o-tolylhex-5-ynal 

Relevant articles and documents

Rhodium-catalyzed intramolecular hydroacylation of 5- and 6-alkynals: Convenient synthesis of α-alkylidenecycloalkanones and cycloalkenones

A novel intramolecular hydroacylation of 5- and 6-alkynals leading to α-alkylidenecycloalkanones was accomplished by using cationic a rhodium(I)/BINAP complex. For all cyclizations described, a single (E)-olefin isomer was obtained. At elevated temperature, hydroacylation and double bond migration of 5- and 6-alkynals proceeded in a one-pot reaction to give cycloalkenones. An intramolecular hydroacylation of a 7-alkynal was unsuccessful. This method represents an attractive new route to highly functionalized α-alkylidenecycloalkanones and cycloalkenones.

Ligand-, copper-, and amine-free sonogashira reaction of aryl iodides and bromides with terminal alkynes

Conditions for an efficient ligand-, copper-, and amine-free palladium-catalyzed Sonogashira reaction of aryl iodides and bromides with terminal alkynes have been developed. Critical to the success of this new protocol is the use of tetrabutylammonium ace