74953-23-4

Basic information

• Product Name: Phenol, 4-(3-bromo-1-propenyl)-2-methoxy-, acetate, (E)-
• CAS NO: 74953-23-4
• Molecular Formula: C12H13BrO3
• Molecular Weight: 285.137
• Mol File: 74953-23-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phenol, 4-(3-bromo-1-propenyl)-2-methoxy-, acetate, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-(3-bromo-1-propenyl)-2-methoxy-, acetate, (E)-(74953-23-4)
• EPA Substance Registry System: Phenol, 4-(3-bromo-1-propenyl)-2-methoxy-, acetate, (E)-(74953-23-4)

Safety Data

• Hazardous Substances Data: 74953-23-4(Hazardous Substances Data)

Upstream product

• 93-28-7 eugenol acetate 
• 5912-87-8 (E)-1-(4-acetoxy-3-methoxyphenyl)-1-propene 

Downstream Products

• 37791-78-9 (2E)-3-(4-O-acetyl-3-methoxyphenyl)prop-2-en-1-yl acetate 
• 94930-70-8 3-(4-acetoxy-3-methoxyphenyl)-3-ethoxy-1-propene 
• 74953-24-5 trans-3-(4-acetoxy-3-methoxyphenyl)-2-propenyl thioacetate 
• 458-35-5 coniferal alcohol 
• 74953-25-6 trans-3-(4-hydroxy-3-methoxyphenyl)-2-propenylthiol 
• 68946-35-0 trans,trans-bis<3-(4-hydroxy-3-methoxyphenyl)-2-propenyl> sulfide 
• 7382-62-9 sodium-1-(4-hydroxy-3-methoxyphenyl)-2-propene-1-sulphonate 
• 104503-89-1 sodium-trans-3-(4-hydroxy-3-methoxyphenyl)-2-propene-1-sulphonate 

Relevant articles and documents

Synthesis of Coniferyl and Dihydroconiferyl Derivatives Using Radical Bromination with N-Bromosuccinimide as the Key Step

Coniferyl and dihydroconiferyl derivatives have been synthesized by reacting bromides, obtained from allylic and benzylic brominations using N-bromosuccinimide (NBS), with appropriate nucleophiles.For instance, NBS bromination of eugenol acetate, followed by replacement of bromine by an acetoxy group and subsequent reduction with lithium aluminium hydride, afforded coniferyl alcohol in 65percent overall yield.Due to the availability of the starting materials (eugenol and isoeugenol) and the good overall yields obtained, these synthetic routes compete well with other methods of preparation.