750624-63-6

Basic information

• Product Name: 4-AMINO-5-(3,5-DIMETHOXYPHENYL)-4H-1,2,4-TRIAZOLE-3-THIOL
• Synonyms: ASISCHEM D13311;4-AMINO-5-(3,5-DIMETHOXYPHENYL)-4H-1,2,4-TRIAZOLE-3-THIOL;4H-1,2,4-triazole-3-thiol, 4-amino-5-(3,5-dimethoxyphenyl);4-amino-5-(3,5-dimethoxyphenyl)-2H-1,2,4-triazole-3-thione
• CAS NO: 750624-63-6
• Molecular Formula: C₁₀H₁₂N₄O₂S
• Molecular Weight: 252.29
• Mol File: 750624-63-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 200 °C(Solv: ethanol (64-17-5))
• Boiling Point: 405.6°C at 760 mmHg
• Flash Point: 199.1°C
• Appearance: /
• Density: 1.45g/cm³
• Vapor Pressure: 8.64E-07mmHg at 25°C
• Refractive Index: 1.675
• PKA: 8.01±0.20(Predicted)
• CAS DataBase Reference: 4-AMINO-5-(3,5-DIMETHOXYPHENYL)-4H-1,2,4-TRIAZOLE-3-THIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-5-(3,5-DIMETHOXYPHENYL)-4H-1,2,4-TRIAZOLE-3-THIOL(750624-63-6)
• EPA Substance Registry System: 4-AMINO-5-(3,5-DIMETHOXYPHENYL)-4H-1,2,4-TRIAZOLE-3-THIOL(750624-63-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 750624-63-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12N4O2S/c1-15-7-3-6(4-8(5-7)16-2)9-12-13-10(17)14(9)11/h3-5H,11H2,1-2H3,(H,13,17)

Upstream product

• 1018856-52-4 C₁₀H₁₁N₂O₃S₂^(1-)*K⁽¹⁺⁾ 

Downstream Products

• 1013750-87-2 C₁₉H₁₈N₄O₃S 
• 1013751-15-9 3-(3,5-dimethoxyphenyl)-6-(3,4-dimethoxyphenyl)-7H-[1,2,4]-triazolo-[3,4-b]-[1,3,4]-thiadiazine 
• 1013751-07-9 C₂₀H₂₀N₄O₄S 
• 578718-93-1 C₁₉H₁₈N₄O₂S 
• 1013751-03-5 C₂₀H₂₀N₄O₄S 
• 922611-23-2 C₁₉H₁₈N₄O₂S 
• 1013793-48-0 C₂₀H₂₀N₄O₄S 
• 1013751-17-1 C₁₉H₁₈N₄O₂S 
• 1013750-99-6 C₁₉H₁₈N₄O₃S 
• 1003848-85-8 6-(2-(5-(2,4-dimethoxyphenyl)-4-amino-4H-1,2,4-triazol-3-ylthio)acetyl)benzo[d]oxazol-2(3H)-one 

Relevant articles and documents

Synthesis, characterization and antimicrobial activities of mercaptoxadiazoles, mercaptotriazoles and their derivatives

Five member heterocycles are famous for their universal activities. Starting with suitably substituted hydrazides 1,3,4-oxadiazole-2-thiones (1-5) and 1,2,4-triazolethionamines (6-11) were synthesized which were later on converted into Mannich products (13-22) and traizolothiadiazines (23-28) respectively. Structures were established by FTIR, hydrogen, carbon NMR, and mass spectrometric analysis. Compounds were evaluated for their antimicrobial studies. Compounds 13, 19 and 23 showed maximum inhibitions in opposition to the bacterial strains while compounds 7, 11, 13 and 27 showed utmost percentage inhibition aligned with the yeast cells.