750634-10-7

Basic information

• Product Name: 5-(3,4-dichloro-benzyl)-2-aza-bicyclo[2.2.2]octane-2-carboxylic acid tert-butyl ester
• Synonyms: 5-(3,4-dichloro-benzyl)-2-aza-bicyclo[2.2.2]octane-2-carboxylic acid tert-butyl ester
• CAS NO: 750634-10-7
• Molecular Weight: 370.319
• Mol File: 750634-10-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(3,4-dichloro-benzyl)-2-aza-bicyclo[2.2.2]octane-2-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3,4-dichloro-benzyl)-2-aza-bicyclo[2.2.2]octane-2-carboxylic acid tert-butyl ester(750634-10-7)
• EPA Substance Registry System: 5-(3,4-dichloro-benzyl)-2-aza-bicyclo[2.2.2]octane-2-carboxylic acid tert-butyl ester(750634-10-7)

Safety Data

• Hazardous Substances Data: 750634-10-7(Hazardous Substances Data)

Upstream product

• 1333-74-0 hydrogen 
• 617714-55-3 5-(3,4-dichlorobenzylidene)-2-aza-bicyclo[2.2.2]octane-2-carboxylic acid tert-butyl ester 
• 4136-97-4 methyl 4-aminosalicylate 
• 2597-56-0 4-nitro-o-anisic acid 
• 13684-28-1 2-hydroxy-4-nitro-benzoic acid methyl ester 
• 619-19-2 2-hydroxy-4-nitrobenzoic acid 
• 750634-09-4 tert-butyl 5-hydroxy-2-azabicyclo[2.2.2]octane-2-carboxylate 
• 617714-22-4 tert-butyl 5-oxo-2-azabicyclo[2.2.2]octane-2-carboxylate 
• 750634-07-2 exo-5-hydroxy-2-azabicyclo-[2.2.2]octan-3-one 
• 794468-38-5 2-aza-bicyclo[2.2.2]octan-5-ol 

Downstream Products

• 617714-23-5 5-(3,4-Dichloro-benzyl)-2-aza-bicyclo[2.2.2]octane 

Relevant articles and documents

Bridged bicyclic amine derivatives useful as CCR-3 receptor antagonists

Compounds having the formula (I), Ar—(F)(E)-(CR3R4)—(CHR5)m-(T)-(Q)-Ar1, are useful as CCR-3 receptor antagonists, wherein T is a bridged heterocyclyl group having one N atom and a bridge of one to two bridgehead carbon atoms; Ar and Ar1 are aryl or heteroaryl; F is alkylene, alkenylene, or a bond; E is —C(═O)N(R10)—, —SO2N(R10)—, —N(R11)C(═O)N(R10O)—, —N(R11)SO2N(R10)—, —N(R11)C(═S)N(R10)—, —N(R11)C(═O)—, —N(R11)SO2—, —N(R12)C(═O)CH(R13)—, or CH(R13)C(═O)N(R12)—; Q is —C(═O)— or C1-2alkylene; and R3, R4, R5, R9, R10, R11, R12, and R13 are defined as set forth in the specification.