75066-70-5Relevant articles and documents
Application of maleimide compound as chitin synthase inhibitor
-
Paragraph 0024-0027; 0056-0059, (2020/07/12)
The invention discloses an application of a maleimide compound as shown in a formula I. In the formula I, R0 is phenyl, benzyl, phenethyl, phenylpropyl, p-fluorophenyl, p-chlorophenyl, p-bromophenyl,p-methoxyphenyl, p-methylphenyl or p-hydroxyphenyl, R1 is hydrogen, methyl, phenyl or chlorine; and R2 is hydrogen, methyl, phenyl or chlorine. The provided maleimide compound has a good inhibition effect on chitin synthase.
Palladium-catalyzed aerobic oxidative carbonylation of alkynes with amines: a general access to substituted maleimides
Yang, Ji,Liu, Jiawang,Jackstell, Ralf,Beller, Matthias
supporting information, p. 10710 - 10713 (2018/09/29)
A catalytic oxidative carbonylation reaction was developed for the synthesis of polysubstituted maleimides from alkynes and amines with air as a green oxidant. This novel transformation proceeds in the presence of palladium chloride without the need for expensive ligands or additives and has a broad substrate scope affording a variety of maleimides in good to high yields.
Hydrogenations without hydrogen: Titania photocatalyzed reductions of maleimides and aldehydes
Manley, David W.,Buzzetti, Luca,MacKessack-Leitch, Andrew,Walton, John C.
, p. 15324 - 15338 (2015/01/16)
A mild procedure for the reduction of electron-deficient alkenes and carbonyl compounds is described. UVA irradiations of substituted maleimides with dispersions of titania (Aeroxide P25) in methanol/acetonitrile (1:9) solvent under dry anoxic conditions led to hydrogenation and production of the corresponding succinimides. Aromatic and heteroaromatic aldehydes were reduced to primary alcohols in similar titania photocatalyzed reactions. A mechanism is proposed which involves two proton-coupled electron transfers to the substrates at the titania surface.