75073-78-8

Basic information

• Product Name: 5-exo,6-endo,7-exo,8-endo-5,6,7,8-tetra(chloroMethyl)-bicyclo[2.2.2]oct-2-ene
• Synonyms: 5-exo,6-endo,7-exo,8-endo-5,6,7,8-tetra(chloroMethyl)-bicyclo[2.2.2]oct-2-ene;5,6,7,8-Tetrakis(chloromethyl)-bicyclo[2.2.2]oct-2-ene
• CAS NO: 75073-78-8
• Molecular Formula: C12H16Cl4
• Molecular Weight: 302.07
• EINECS: -0
• Mol File: 75073-78-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-exo,6-endo,7-exo,8-endo-5,6,7,8-tetra(chloroMethyl)-bicyclo[2.2.2]oct-2-ene(CAS DataBase Reference)
• NIST Chemistry Reference: 5-exo,6-endo,7-exo,8-endo-5,6,7,8-tetra(chloroMethyl)-bicyclo[2.2.2]oct-2-ene(75073-78-8)
• EPA Substance Registry System: 5-exo,6-endo,7-exo,8-endo-5,6,7,8-tetra(chloroMethyl)-bicyclo[2.2.2]oct-2-ene(75073-78-8)

Safety Data

• Hazardous Substances Data: 75073-78-8(Hazardous Substances Data)

Upstream product

• 120664-28-0 (1r,2R,3R,4s,5S,6S)-bicyclo<2.2.2>oct-7-ene-2,3,5,6-tetramethanol 
• 62234-71-3 (+/-)-exo-2,endo-3,exo-5,endo-6-tetrakis(hydroxymethyl)bicyclo<2.2.2>oct-7-ene 
• 3573-76-0 (1r,2R,3S,4r,5R,6S)-bicyclo<2.2.2>oct-2-ene-2,3,5,6-tetracarboxylic bisanhydride 
• 56745-93-8 2,3,5,6-exo-bicyclo<2.2.2>-7-octene-2,3,5,6-tetracarboxylic acid tetramethyl ester 
• 56745-93-8 tetramethyl all-trans-bicyclo[2.2.2]oct-7-ene-2,3,5,6-tetracarboxylate 
• 62234-71-3 5-exo,6-endo,7-exo,8-endo-5,6,7,8-tetra(hydroxymethyl)bicyclo[2.2.2]oct-2-ene 
• 56782-36-6 2,6-exo-3,5-endo-bicyclo<2.2.2>-7-octene-2,3,5,6-tetracarboxylic acid tetramethyl ester 

Downstream Products

• 62234-75-7 5,6,7,8-tetramethylenebicyclo[2.2.2]oct-2-ene 

Relevant articles and documents

Extremely large cavity assembled by self-interlocking of distorted biconcave porphyrins

X-Ray analyses of free base, zinc, and nickel complexes of 2,3;7,8;12,13;17,18-tetrakis(6,13-dihydro-6,13-pentaceno)-21H,23H-porphine revealed that the porphyrin chromophores adopted a heavily-saddled conformation by interlocking of the biconcave porphyrins in the crystals containing halobenzenes as crystalline solvents, while the ring was almost flat in the crystals obtained from benzene or from chlorobenzene and isopropanol.

Tandem Diels-Alder Reactivity Controlled by Remote Substituents. Regioselective Synthesis of Linearly Annellated Six-Membered Ring Systems from (1RS,5SR,6RS,7SR)-6,7-Bis(chloromethyl)-8,9-dimethylidene-2-oxabicyclononan-3-one. Crystal Structure of

Syntheses of 6,7,8,9-tetramethylidene-2-oxabicyclononan-3-one (12), 6,7,8,9-tetramethylidene-2-azatricyclononan-3-one (13), and (1RS,5SR,6RS,7SR)-6,7-bis(chloromethyl)-8,9-dimethylidene-2-oxabicyclononan-3-one (14) are presented.The r

THE 7,8-EPOXY2,3,5,6-TETRAKIS(METHYLENE)BICYCLOOCTANE; SYNTHESIS AND DIELS-ALDER REACTIVITY

The preparation of 7,8-epoxy-2,3,5,6-tetrakis(methylene)bicyclooctane (5) is described.Evidence for transannular interaction between the homoconjugated s-cis-butadiene functions in 5 is found in the UV absorption spectrum.The Diels-Alder addition of 5 to tetracyanoethylene (TCE) is syn-regioselective and leads to the monoadducts 16:17 (85:15).The dienes 16, 17 are less reactive then 5 toward TCE. anti-regioselectivity (leading to exo-2, endo-3-bis(chloromethyl)-5,6-bis(methylene)-syn-7,8-epoxybicyclooctanes) (25) is observed in the double elimination of HCl from the syn-7,8-epoxy-exo-2,endo-3,exo-5,endo-6-tetrakis(chloromethyl)bicyclooctane (11), precursor of 5.The structure of the regioisomers 16, 17 were confirmed spectroscopically and chemically.Elimination of HCl from the chloromethyl groups in 26 (TCE adduct of 25) and HCN from the TCE adducts 16, 17 and 26 can be induced by CsF in DMF.