7511-27-5

Basic information

• Product Name: 1-bromo-7-methylnaphthalene
• CAS NO: 7511-27-5
• Molecular Formula: C₁₁H₉Br
• Molecular Weight: 221.0932
• Mol File: 7511-27-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 301.2°C at 760 mmHg
• Flash Point: 137.6°C
• Density: 1.417g/cm³
• Vapor Pressure: 0.00191mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: 1-bromo-7-methylnaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-7-methylnaphthalene(7511-27-5)
• EPA Substance Registry System: 1-bromo-7-methylnaphthalene(7511-27-5)

Safety Data

• Hazardous Substances Data: 7511-27-5(Hazardous Substances Data)

Usage

General Description

1-bromo-7-methylnaphthalene is a chemical compound with the formula C11H9Br. It is a derivative of naphthalene, containing a bromine atom at the 1-position and a methyl group at the 7-position. 1-bromo-7-methylnaphthalene is used as a reagent in organic synthesis, particularly in the preparation of various substituted naphthalene derivatives. It is also used in the production of pharmaceuticals, agrochemicals, and dyes. Due to its bromine atom, 1-bromo-7-methylnaphthalene is a potential source of chemical reactivity and is often employed in the formation of carbon-carbon and carbon-heteroatom bonds in synthetic organic chemistry. However, it should be handled with caution due to its potential health hazards and environmental impact.

Upstream product

• 76-84-6 triphenylmethyl alcohol 
• 127810-66-6 8-bromo-2-hydroxy-2-methyl-1,2,3,4-tetrahydronaphthalene 
• 412041-50-0 1,2-diethynyl-4-methylbenzene 

Downstream Products

• 98331-28-3 7-Methoxymethyl-1-(3-methoxymethyl-phenoxy)-naphthalene 
• 98331-29-4 7-Bromomethyl-1-(3-bromomethyl-phenoxy)-naphthalene 
• 135942-96-0 1-cyano-7-(bromomethyl)naphthalene 
• 35387-22-5 7-Methyl-[1]naphthoesaeure 
• 841259-41-4 8-bromonaphthalene-2-carbaldehyde 
• 98331-27-2 8-bromo-2-(bromomethyl)naphthalene 
• 38879-97-9 7-methylnaphthalene-1-carbonitrile 

Relevant articles and documents

Regioselective haloaromatization of 1,2-bis(ethynyl)benzene via halogen acids and PtCl2. Platinum-catalyzed 6-π electrocyclization of 1,2-bis(1′-haloethenyl)benzene intermediates

Treatment of 1,2-bis(ethynyl)benzene (1) with aqueous HX (X = Br, I) in hot 3-pentanone (100-105 °C, 2 h) afforded 1,2-bis(1′-haloethenyl)benzene species 2-Br and 2-I in 98% and 95% yields, respectively. The hydrochlorination of endiyne 1 failed to proceed at elevated temperature but was implemented efficiently by PtCl2 (5 mol %) in hot 3-pentanone (100 °C, 2 h) to give 1,2-bis(1′-chloroetheny)benzene 2-Cl in 80% yield. In the presence of PtCl2 (5 mol %), these halides 2-Cl, 2-Br, and 2-I were subsequently converted to 1-halonaphthalenes 3-Cl, 3-Br, and 3-I in the mother solution via sequential 6-π electrocyclization and dehalogenation reactions. PtCl2 (5 mol %) also effected direct haloaromatization of endiyne 1 with HX (X = Cl, Br, I) and gave 1-halonaphthalenes 3-Cl, 3-Br, and 3-I in 64-71% yields. This investigation reports the scope and the regioselectivity of haloaromatization of various enediynes catalyzed by PtCl2.

Processes for the preparation of novel naphthalenylmethyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents

This invention relates to the processes for the production of novel [(substituted naphthalenyl)methyl]-3H-1,2,3,5-oxathiadiazole 2-oxides. The compounds have pharmaceutical properties which render them beneficial for the treatment of diabetes mellitus and