75120-94-4Relevant articles and documents
Heteroatom-embedded medium-sized cycloalkynes: Concise synthesis, structural analysis, and reactions
Ni, Runyan,Mitsuda, Naoto,Kashiwagi, Takeru,Igawa, Kazunobu,Tomooka, Katsuhiko
, p. 1190 - 1194 (2015)
A variety of medium-sized cycloalkynes were efficiently synthesized by the double Nicholas reaction of cobalt complex and bis(hetero)substituted acyclic compound. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. Furthermore, preparation of multifunctionalized alkynes was achieved by embedding the cycloalkyne within a peptide chain.
Dynamic Protection of Amines using 18-Crown-6
Barrett, Anthony G. M.,Lana, J. Carlos A.,Tograie, Shahrzad
, p. 300 - 301 (2007/10/02)
The regioselectivity of diamine monoacylation has been controlled by selective complexation with 18-crown-6 and a proton source.