75121-05-0Relevant articles and documents
Design, Palladium-Catalyzed Synthesis, and Biological Investigation of 2-Substituted 3-Aroylquinolin-4(1H)-ones as Inhibitors of the Hedgehog Signaling Pathway
Alfonsi, Romina,Botta, Bruno,Cacchi, Sandro,Di Marcotullio, Lucia,Fabrizi, Giancarlo,Faedda, Roberta,Goggiamani, Antonella,Iazzetti, Antonia,Mori, Mattia
, p. 1469 - 1477 (2017/03/08)
2-Substituted 3-aroylquinolin-4(1H)-ones, prepared through a palladium-catalyzed carbonylative cyclization of N-(2-iodoaryl)enaminones, proved to inhibit efficiently the Hedgehog pathway through direct antagonism of the wild-type and drug-resistant form o
3-Aroylindoles via copper-catalyzed cyclization of N-(2-iodoaryl)enaminones
Bernini, Roberta,Cacchi, Sandro,Fabrizi, Giancarlo,Filisti, Eleonora,Sferrazza, Alessio
experimental part, p. 1480 - 1484 (2009/10/17)
3-Aroylindoles have been prepared via copper-catalyzed cyclization of N-(2-iodoaryl)enaminones, readily available from 2-iodoanilines and α,β-ynones. The reaction tolerates a variety of useful functionalities including ether, keto, cyano, bromo, and chlor
Photocyclization of Aryl Halides. Part 2. The Upper Excited State Reactivity of 3-(2-Halogenoanilino)-1,3-diphenylprop-2-enones; Hydrogen-bonded Configurational Lock in Photosynthesis
Grimshaw, James,de Silva, A. Prasanna
, p. 1010 - 1014 (2007/10/02)
Photocyclization of the internally hidrogen-bonded dibenzoylmethane 2-bromo- and 2-iodo-anils proceed cleanly, though with low quantum yield, to afford a phenanthridine derivative directly and with very little competition from hydrogen abstraction reactio
