75158-11-1

Basic information

• Product Name: 2-<(S)-α-methylbenzylamino>-3,3,dimethylbutyramide
• Synonyms: 2-<(S)-α-methylbenzylamino>-3,3,dimethylbutyramide
• CAS NO: 75158-11-1
• Molecular Weight: 234.341
• Mol File: 75158-11-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-<(S)-α-methylbenzylamino>-3,3,dimethylbutyramide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-<(S)-α-methylbenzylamino>-3,3,dimethylbutyramide(75158-11-1)
• EPA Substance Registry System: 2-<(S)-α-methylbenzylamino>-3,3,dimethylbutyramide(75158-11-1)

Safety Data

• Hazardous Substances Data: 75158-11-1(Hazardous Substances Data)

Upstream product

• 2627-86-3 (S)-1-phenyl-ethylamine 
• 630-19-3 pivalaldehyde 
• 33978-37-9 1-<(S)-α-methylbenzylimino>-2,2-dimethylpropane 
• 75158-10-0 (S,S)-3,3-dimethyl-2-(1-phenylethylamino)butyronitrile 
• 17279-30-0 (S)-(-)-α-methylbenzylamine hydrochloride 

Downstream Products

• 20859-02-3 L-tert-Leucine 
• 63038-27-7 L-tert-leucine methyl ester hydrochloride 
• 75158-13-3 t-butoxycarbonyl-L-phenylalanyl-L-t-butylglycine amide 
• 75158-14-4 t-butoxycarbonyl-L-tyrosyl-D-alanyl-glycyl-L-phenylalanyl-L-t-butylglycine amide 
• 63038-26-6 (S)-2-amino-3,3-dimethyl-butyric acid methyl ester 
• 62965-57-5 (S)-(+)-2-amino-3,3-dimethylbutanamide 

Relevant articles and documents

Optically active iminocarboxylic acid derivatives

The compounds of the formula STR1 wherein R is OH, NH2, lower-alkyl-NH or phenyl-lower alkyl-NH are presented. These compounds can be catalytically hydrogenated to the corresponding α-aminocarboxylic acid derivatives which are intermediates in the synthesis of therapeutic pseudopeptides.

Synthesis, enzymic degradation, lipophilic properties, and biological activity of [D-alanine2, t-butylglycine 5]enkephalin amide

L-C(a)-t-Butylglycine (Bug), its amide, methyl ester, and N(a)-t-butoxycarbonyl derivative were prepared by an asymmetric synthesis, and the Hansch side-chain hydrophobic (lipophilicity) parameter determined. A new enkephalin analogue, H . Tyr-D-Ala-Gly-Phe-Bug . HN2 was synthesized which is pharmacologically active in two in vitro assays and strongly resistant against a number of enzymes in vitro.