75191-44-5Relevant articles and documents
Inhibition of dihydrofolate reductase. 3. 4,6-Diamino-1,2-dihydro-2,2-dimethyl-1-(2-substituted-phenyl)-s-triazine inhibition of bovine liver and mouse tumor enzymes
Kim,Dietrich,Hansch,Dolnick,Bertino
, p. 1248 - 1251 (1980)
Inhibition of dihydrofolate reductase from bovine liver and murine L5178YR-C3 tumor cells has been examined for a series of 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(2-X-phenyl)s-triazines. For both enzymes all 2-X substituents cause a decrease i