75225-11-5

Basic information

• Product Name: N-tert-Butyl-N'-(3-trifluoromethyl-phenyl)-acrylamidine
• Synonyms: N-tert-Butyl-N'-(3-trifluoromethyl-phenyl)-acrylamidine
• CAS NO: 75225-11-5
• Molecular Weight: 270.298
• Mol File: 75225-11-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-tert-Butyl-N'-(3-trifluoromethyl-phenyl)-acrylamidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-Butyl-N'-(3-trifluoromethyl-phenyl)-acrylamidine(75225-11-5)
• EPA Substance Registry System: N-tert-Butyl-N'-(3-trifluoromethyl-phenyl)-acrylamidine(75225-11-5)

Safety Data

• Hazardous Substances Data: 75225-11-5(Hazardous Substances Data)

Upstream product

• 507-20-0 tertiary butyl chloride 
• 98-16-8 3-trifluoromethylaniline 
• 107-13-1 acrylonitrile 

Downstream Products

• 80281-71-6 N-tert-Butyl-3-cyclohexylamino-N'-(3-trifluoromethyl-phenyl)-propionamidine 
• 80252-43-3 N-tert-Butyl-3-methoxy-N'-(3-trifluoromethyl-phenyl)-propionamidine 

Relevant articles and documents

SYNTHESE DE NOUVELLES PROPENAMIDINES N-SUBSTITUEES A PARTIR DE SELS DE NITRILIUM

A number of N-t-butylpropenamidines V have been prepared for the first time by amination of N-t-butylacrylonitrilium (IIIb) or N-t-butylmethacrylonitrilium tetrachloroferrate (IIIc).The salts IIIb and IIIc are easily prepared at -40 deg C within a few minutes from the corresponding nitrile, t-butyl chloride and ferric chloride.The amination (with primary or secondary aliphatic or aromatic amines) should be started at -70 deg C to ensure a smooth reaction and to give high yields of amidine V, because the nitrilium salts are unstable above -10 deg C.This method represents an easy one-pot synthesis of N-t-butyl substituted propenamidines from the corresponding nitrile I.