7530-16-7

Basic information

• Product Name: 1-(2-cyclohexyl-ethyl)-piperidine
• Synonyms: 1-(2-cyclohexyl-ethyl)-piperidine
• CAS NO: 7530-16-7
• Molecular Weight: 195.348
• Mol File: 7530-16-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(2-cyclohexyl-ethyl)-piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-cyclohexyl-ethyl)-piperidine(7530-16-7)
• EPA Substance Registry System: 1-(2-cyclohexyl-ethyl)-piperidine(7530-16-7)

Safety Data

• Hazardous Substances Data: 7530-16-7(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 931-48-6 2-cyclohexylacetylene 
• 81816-90-2 1-((E)-2-Cyclohexyl-vinyl)-piperidine 
• 39742-60-4 1-(2-phenylethyl)-4-piperidinone 
• 1647-26-3 1-bromo-2-cyclohexylethane 

Relevant articles and documents

2:1 versus 1:1 Coupling of Alkylacetylenes with Secondary Amines: Selectivity Switching in 8-Quinolinolato Rhodium Catalysis

Both 2:1 and 1:1 couplings of alkylacetylenes with secondary amines were achieved using 8-quinolinolato rhodium catalysts and CsF. The 2:1/1:1 selectivity was switched by choosing the reaction solvent. In DMA, an unprecedented 2:1 coupling reaction of alkylacetylenes with amines proceeded to give 2-aminodiene products. One-pot 2:1 coupling/reduction provided rapid access to various allylamines, while one-pot coupling/hydrolysis gave enones as products. In toluene, anti-Markovnikov hydroamination occurred under relatively mild conditions to give 1:1 coupling products.