75349-23-4

Basic information

• Product Name: (3-METHYL-PIPERAZIN-1-YL)-PHENYL-METHANONE
• Synonyms: (3-METHYL-PIPERAZIN-1-YL)-PHENYL-METHANONE;(R)-4-BENZOYL-2-METHYLPIPERAZINE HCI;Methanone, (3-methyl-1-piperazinyl)phenyl-;1-benzoyl-3-methylpiperazine
• CAS NO: 75349-23-4
• Molecular Formula: C₁₂H₁₆N₂O
• Molecular Weight: 204.27
• Mol File: 75349-23-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 345.326 °C at 760 mmHg
• Flash Point: 162.648 °C
• Appearance: /
• Density: 1.072 g/cm³
• CAS DataBase Reference: (3-METHYL-PIPERAZIN-1-YL)-PHENYL-METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (3-METHYL-PIPERAZIN-1-YL)-PHENYL-METHANONE(75349-23-4)
• EPA Substance Registry System: (3-METHYL-PIPERAZIN-1-YL)-PHENYL-METHANONE(75349-23-4)

Safety Data

• Hazardous Substances Data: 75349-23-4(Hazardous Substances Data)

Usage

General Description

(3-Methyl-piperazin-1-yl)-phenyl-methanone is a chemical compound that belongs to the group of phenyl ketones. It is a potential drug candidate with various pharmacological activities, mainly as a central nervous system (CNS) stimulant and an antidepressant. (3-METHYL-PIPERAZIN-1-YL)-PHENYL-METHANONE has been studied for its potential use in the treatment of neurological disorders and mood disorders. Its chemical structure and properties make it suitable for further research and development as a potential drug candidate for therapeutic use.

Upstream product

• 98-88-4 benzoyl chloride 
• 109-07-9 (RS)-2-methylpiperazine 
• 300561-20-0 N-benzoyl-N-(2,3,4,5,6-pentafluorophenyl)methanesulfonamide 
• 213327-29-8 2-chloro-N,N-dibenzoylaniline 
• 215657-47-9 N-benzoyl-N-(2-fluorophenyl)methanesulfonamide 
• 93-97-0 benzoic acid anhydride 

Downstream Products

• 1357376-37-4 C₂₂H₂₀N₄O₅ 
• 948990-58-7 5-(4-benzoyl-2-methyl-piperazine-1-sulfonyl)-thiophene-2-carboxylic acid ethyl ester 
• 948990-63-4 [4-(3-bromo-benzenesulfonyl)-3-methyl-piperazin-1-yl]-phenyl-methanone 
• 948990-60-1 [4-(5-bromo-thiophene-2-sulfonyl)-3-methyl-piperazin-1-yl]-phenyl-methanone 
• 1001411-95-5 (+/-)-[4-(7-chloro-1H-pyrrolo[2,3-c]pyridine-3-sulfonyl)-3-methylpiperazin-1-yl]phenylmethanone 
• 1001411-93-3 C₁₉H₁₈Cl₂N₄O₃S 
• 1001411-91-1 C₂₀H₂₂N₄O₄S 

Relevant articles and documents

PIPERAZINE DERIVATIVES AS ANTIVIRAL AGENTS WITH INCREASED THERAPEUTIC ACTIVITY

The present invention provides 2-phenylpiperazine derivatives having a benzofuran-2-yl group which contributes to increase the antiviral activity as well as, for some substituents, the CC50, giving more active and less cytotoxic compounds. Alth

Studies on development of sufficiently chemoselective N-acylation reagents: N-Acyl-N-(2,3,4,5,6-pentafluorophenyl)methanesulfonamides

A variety of storable N-acyl-N-(2,3,4,5,6-pentafluorophenyl)methanesulfonamides (4a-e) prepared from N-2,3,4,5,6-pentafluorophenylmethanesulfonamide (3), have been developed after systematic research on the structure-reactivity relationship and were found to serve as N-acylation reagents exhibiting sufficiently good chemoselectivity. (C) 2000 Elsevier Science Ltd.

Regioselective Monobenzoylation of Unsymmetrical Piperazines

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