75443-99-1

Basic information

• Product Name: ACLARUBICIN HYDROCHLORIDE
• Synonyms: ACLARUBICIN HYDROCHLORIDE;aclacinomycinahydrochloride;aclacinon;n-2-yl)-alpha-l-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-l-lyxo-hexopyrano;syl)oxy)-2,5,7-trihydroxy-,methylester,hydrochloride,(1r-(1-alpha,2-beta,4;1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-alpha-l-lyxo-hexopyranosyl]-3-(dimethylamino)-alpha-l-lyxo;1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]-3-(dimethylamino)-α-L-lyxo-hexopyranosyl]oxy]-, meth;1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]-3-(dimethylamino)-α-L-lyxo-hexopyranosyl]oxy]-, methyl ester, hydrochloride, [1R-(1α,2β,4β)]-
• CAS NO: 75443-99-1
• Molecular Formula: C42H54ClNO15
• Molecular Weight: 848.33
• EINECS: 278-209-3
• Product Categories: API
• Mol File: 75443-99-1.mol
• Article Data: 0

Chemical Properties

• Melting Point: 151-153℃
• Boiling Point: 898℃
• Flash Point: >110°(230°F)
• Appearance: /
• Vapor Pressure: 1.17E-34mmHg at 25°C
• Storage Temp.: 2-8°C
• Solubility: Soluble in DMSO or DMF at 25mg/ml
• CAS DataBase Reference: ACLARUBICIN HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: ACLARUBICIN HYDROCHLORIDE(75443-99-1)
• EPA Substance Registry System: ACLARUBICIN HYDROCHLORIDE(75443-99-1)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25
• Safety Statements: 36/37/39-45
• RIDADR: 3249
• RTECS: QI9283500
• HazardClass: 6.1(a)
• PackingGroup: II
• Hazardous Substances Data: 75443-99-1(Hazardous Substances Data)

Usage

General Description

Aclarubicin hydrochloride is a chemotherapy drug used to treat various types of cancer, including leukemia and certain types of solid tumors. It is a synthetic anthracycline antibiotic that works by interfering with the growth and spread of cancer cells in the body. Aclarubicin hydrochloride works by binding to the DNA of cancer cells, causing breaks in the DNA strands and ultimately leading to cell death. It is administered intravenously by a healthcare professional and is typically used in combination with other cancer medications. Common side effects of aclarubicin hydrochloride may include nausea, vomiting, hair loss, and a lowered white blood cell count. Regular blood tests are required during treatment to monitor for potential side effects.

InChI:InChI=1/C42H53NO15.ClH/c1-8-42(51)17-28(33-22(35(42)41(50)52-7)14-23-34(38(33)49)37(48)32-21(36(23)47)10-9-11-26(32)45)56-30-15-24(43(5)6)39(19(3)54-30)58-31-16-27(46)40(20(4)55-31)57-29-13-12-25(44)18(2)53-29;/h9-11,14,18-20,24,27-31,35,39-40,45-46,49,51H,8,12-13,15-17H2,1-7H3;1H/t18-,19-,20-,24-,27-,28-,29-,30-,31-,35-,39+,40+,42+;/m0./s1