75445-61-3Relevant articles and documents
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Arbuzov,Yu.A. et al.
, (1964)
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Enantioselective Total Synthesis of (?)-Spiroxins A, C, and D
Chen, Chong-Chong,Hu, Xiangdong,Shu, Xin,Yang, Jiayi,Yu, Tao
supporting information, p. 18514 - 18518 (2021/07/20)
Spiroxins A, C, and D are metabolites that have been identified in the marine fungal strain LL-37H248. Their unique polycyclic structures and intriguing biological activities make them attractive targets for the synthetic community. Based on a scalable en
Enzymatic desymmetrization/resolution of epoxydiols derived from 1,4-naphthoquinone, 5-hydroxy-1,4-naphthoquinone and 5,8-dihydroxy-1,4- naphthoquinone
Betts, Russell L.,Murphy, Sean T.,Johnson, Carl R.
, p. 2853 - 2860 (2007/10/03)
The enzymatic desymmetrization/resolution of epoxydiols generated from the basic epoxidation and reduction of 1,4-naphthoquoinone, 5-hydroxy-1,4- naphthoquinone and 5,8-dihydroxy-1,4-naphthoquinone is described. 2,3-Epoxy-1α,2α,3α,4 α-tetrahydronaphthalene-1,4-diol and 5,8-diallyloxy-2,3-epoxy- 1α,2α,3α,4 α-tetrahydronaphthalene-1,4-diol were desymmetrized in the presence of isopropenyl acetate using Burholderia cepacia lipase and Candida antartica lipase B, respectively. An enzymatic resolution of 8-benzyloxy-2,3-epoxy-1α,2α,3 α,4α-tetrahydronaphthalene-1,4-diol using B. cepacia lipase in isopropenyl acetate is also described.