75483-32-8 Usage
Structure
Consists of a piperidine ring and a pyrrolidone ring.
Explanation
The compound is formed by the fusion of a six-membered piperidine ring and a five-membered pyrrolidone ring.
Explanation
The compound's unique structure allows it to react with various other molecules, making it a valuable component in the synthesis of more complex organic compounds.
Explanation
The compound's reactivity and structure contribute to its potential as a therapeutic agent, as it can be modified to create drugs with desired pharmacological effects.
Explanation
Research suggests that the compound may have calming effects on the central nervous system, which could be useful in treating anxiety and other related conditions.
Explanation
The compound may help to alleviate muscle tension and spasms, making it a potential treatment for muscle-related conditions.
Explanation
The compound's effects on the central nervous system may make it a promising candidate for the treatment of epilepsy and neurodegenerative diseases, although further studies are needed.
Explanation
While the compound has shown promise in various areas, more research is required to determine its efficacy and safety as a therapeutic agent.
Versatile reactivity
Commonly used as a building block in organic synthesis.
Pharmacological properties
Used in drug development.
Central nervous system depressant potential
Studied for its potential as a CNS depressant.
Muscle relaxant potential
Studied for its potential as a muscle relaxant.
Potential applications in epilepsy and neurodegenerative diseases
Research has shown its potential in treating these conditions.
Therapeutic potential and safety profile
Further studies are needed to fully understand its potential and safety.
Check Digit Verification of cas no
The CAS Registry Mumber 75483-32-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,4,8 and 3 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 75483-32:
(7*7)+(6*5)+(5*4)+(4*8)+(3*3)+(2*3)+(1*2)=148
148 % 10 = 8
So 75483-32-8 is a valid CAS Registry Number.
75483-32-8Relevant articles and documents
SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1
-
, (2018/01/20)
The invention is directed to substituted pyridine derivatives. Specifically, the invention is directed to compounds according to Formula (Iar): (Iar) wherein Yar, X1ar, X2ar, R1ar, R2ar, R3ar, R4ar and R5ar are as defined herein; or a pharmaceutically acceptable salt or prodrug thereof. The compounds of the invention are selective inhibitors of DNMT1 and can be useful in the treatment of cancer, pre-cancerous syndromes, beta hemoglobinopathy disorders, sickle cell disease, sickle cell anemia, and beta thalassemia, and diseases associated with DNMT1 inhibition. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting DNMT1 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.
Design and optimization of tricyclic phtalimide analogues as novel inhibitors of HIV-1 integrase
Verschueren, Wim G.,Dierynck, Inge,Amssoms, Katie I. E.,Hu, Lili,Boonants, Paul M. J. G.,Pille, Geert M. E.,Daeyaert, Frits F. D.,Hertogs, Kurt,Surleraux, Dominique L. N. G.,Wigerinck, Piet B. T. P.
, p. 1930 - 1940 (2007/10/03)
Human immunodeficiency virus type-1 integrase is an essential enzyme for effective viral replication and hence a valid target for the design of inhibitors. We report here on the design and synthesis of a novel series of phthalimide analogues as integrase
