75498-96-3

Basic information

• Product Name: (6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt
• Synonyms: Cefminox sodium; MT-141; Alteporina; Tencef; Meicelin; 7beta-[2-[2(S)-Amino-2-carboxyethylthio]acetamido]-7alpha-methoxy-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid sodium salt; 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-[[(2S)-2-amino-2-carboxyethyl]thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt, (6R,7S)- (1:1); (6R,7S)-7-[[[[(2S)-2-Amino-2-carboxyethyl]thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt; 6R,7S)-7-[[[[(2S)-2-Amino-2-carboxyethyl]thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt; (6r-(6alpha,7alpha))-7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt
• CAS NO: 75498-96-3
• Molecular Formula: C₁₆H₂₀N₇O₇S₃*Na
• Molecular Weight: 540.54953
• Mol File: 75498-96-3.mol
• Article Data: 1

Chemical Properties

• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• CAS DataBase Reference: (6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: (6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt(75498-96-3)
• EPA Substance Registry System: (6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt(75498-96-3)

Safety Data

• Hazardous Substances Data: 75498-96-3(Hazardous Substances Data)

Usage

Description

(6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt is a complex organic compound with a unique chemical structure. It is characterized by its 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid backbone, which is modified with various functional groups, including a monosodium salt, a methoxy group, a tetrazol-5-ylthio group, and an amino-carboxyethylthioacetyl group. (6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt is likely to have specific applications in various fields due to its unique chemical properties.

Uses

1. Used in Pharmaceutical Industry:
(6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt is used as a pharmaceutical compound for its potential therapeutic applications. (6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt's unique structure may allow it to interact with specific biological targets, making it a candidate for the development of new drugs.
2. Used in Chemical Research:
In the field of chemical research, this compound can be used as a starting material or a building block for the synthesis of other complex organic molecules. Its unique functional groups and structural features make it an interesting subject for further study and potential applications in various chemical processes.
3. Used in Material Science:
(6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt's unique chemical structure may also find applications in material science, where it could be used to develop new materials with specific properties. For example, its potential to form complexes with other molecules or its ability to interact with biological targets could be exploited in the design of novel materials for various applications.

Synthetic route

l-cysteine hydrochloride (52-89-1) + 7β-chloroacetamido-7α-methoxy-3-(1-methyl-1H-tetrazole-5-mercaptomethyl)-3-cephem-4-carboxylic acid (57617-09-1) → (6R,7S)-7-[(S)-2-(2-amino-2-carboxyethylmercapto)acetamido]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (75498-96-3)

Conditions	Yield
With ethylenediaminetetraacetic acid; sodium thiosulfate In water at 50℃; Concentration; Temperature;	97.9%

Upstream product

• 52-89-1 l-cysteine hydrochloride 
• 57617-09-1 7β-chloroacetamido-7α-methoxy-3-(1-methyl-1H-tetrazole-5-mercaptomethyl)-3-cephem-4-carboxylic acid 

Relevant articles and documents

Cefminox sodium compound reducing adverse reactions and preparation thereof

The invention relates to an antibiotic drug, in particular to a preparation process of cefminox sodium compound reducing adverse reactions and a preparation of the cefminox sodium compound. The preparation process has the advantages such as high yield and high purity and is suitable for industrial production, and an obtained product has significant improvements in terms of product stability, preparations to reduce adverse reactions, and clinical application.