75499-78-4Relevant articles and documents
Chemical Transformation of Protoberberines. Part 10. A Novel Synthesis of Sanguilutine and Dihydrosanguilutine, fully Aromatised 2,3,7,8,10-Pentaoxygenated Benzophenanthridine Alkaloids
Hanaoka, Miyoji,Kobayashi, Nobuyuki,Shimada, Ken-ichi,Mukai, Chisato
, p. 677 - 682 (2007/10/02)
2,3,7,8,10-Pentaoxygenated benzophenanthridine alkaloids, sanguilutine (1) and dihydrosanguilutine (2), were efficiently synthesized from the corresponding 2,3,9,10,12-pentamethoxyprotoberberine (8) through a regioselective C(6)-N bond cleavage, followed by recombination between the original C(6) and C(13) positions of compound (8) according to a biomimetic route.