755039-88-4

Basic information

• Product Name: Benzenemethanamine, N-[cis-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-N-(phenylmeth yl)-
• CAS NO: 755039-88-4
• Molecular Formula: C28H39N3
• Molecular Weight: 417.638
• Mol File: 755039-88-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, N-[cis-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-N-(phenylmeth yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, N-[cis-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-N-(phenylmeth yl)-(755039-88-4)
• EPA Substance Registry System: Benzenemethanamine, N-[cis-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-N-(phenylmeth yl)-(755039-88-4)

Safety Data

• Hazardous Substances Data: 755039-88-4(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 373608-50-5 4-cyclopropylmethylpiperazine-1-carboxylic acid tert-butyl ester 
• 27489-62-9 trans-4-hydroxycyclohexylamine 
• 57184-25-5 1-cyclopropylmethylpiperazine 
• 149506-79-6 4-(dibenzylamino)cyclohexanone 
• 373608-42-5 1-(cyclopropylmethyl)piperazine dihydrochloride 
• 50910-54-8 trans-4-aminocyclohexanol hydrochloride 
• 149506-81-0 trans-4-(dibenzylamino)cyclohexanol 

Downstream Products

• 1280665-47-5 N-[(cis)-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl]-7-[[(7R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-2,3-dihydrobenzofuran-4-carboxamide 
• 1280665-46-4 N-[(cis)-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl]-7-[[(7S)-7-ethyl-8-isopropyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-2,3-dihydrobenzofuran-4-carboxamide 
• 1280665-14-6 7-[[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-N-[(cis)-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl]-2,2-dimethyl-3H-benzofuran-4-carboxamide 
• 1280664-94-9 7-[[(7R)-8-Cyclopentyl-7-ethyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-N-[(cis)-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl]-2,3-dihydrobenzofuran-4-carboxamide 
• 755039-90-8 (cis)-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexanamine 
• 882660-42-6 cis-4-(4-cyclopropylmethylpiperazin-1-yl)-cyclohexylamine trihydrochloride 

Relevant articles and documents

CYCLIN-DEPENDENT KINASE INHIBITING COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS

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DIHYDROPTERIDINONE DERIVATIVES, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF

Dihydroperidinone derivatives, preparation process and pharmaceutical use thereof are disclosed. Specially, new dihydroperidinone derivatives represented by general formula (I), wherein each substituent of the general formula (I) is defined as in the description, their preparation process, pharmaceutical compositions comprising said derivatives and their use as therapeutical agents, especially as Plk kinase inhibitors are disclosed.

DIHYDROPTERIDINONES, METHOD FOR THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS

The invention relates to novel dihydropteridinones of general formula (I), wherein rests L, R1-R5 have the significance indicated in claims and a specification, in the isomers thereof, in a method for producing and using said dihydropteridinones in the form of drugs.