7560-69-2

Basic information

• Product Name: 1-cyclohexyl-2-propyn-1-one
• Synonyms: 1-cyclohexyl-2-propyn-1-one
• CAS NO: 7560-69-2
• Molecular Weight: 136.194
• Mol File: 7560-69-2.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: 1-cyclohexyl-2-propyn-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-cyclohexyl-2-propyn-1-one(7560-69-2)
• EPA Substance Registry System: 1-cyclohexyl-2-propyn-1-one(7560-69-2)

Safety Data

• Hazardous Substances Data: 7560-69-2(Hazardous Substances Data)

Upstream product

• 17715-00-3 prop-2-ynylcyclohexane 
• 2043-61-0 cyclohexanecarbaldehyde 
• 1066-54-2 trimethylsilylacetylene 
• 80783-98-8 N-methoxy-N-methylcyclohexanecarboxamide 
• 2719-27-9 cyclohexanylcarbonyl chloride 
• 62455-70-3 3-cyclohexyl-3-oxopropanenitrile 
• 97563-45-6 1-cyclohexylprop-2-yn-1-ol 

Downstream Products

• 644-46-2 allomaltol 
• 105881-33-2 C₃₈H₅₃NO₅Si 
• 105880-47-5 C₃₈H₅₃NO₅Si 
• 105880-46-4 C₃₈H₅₃NO₅Si 
• 105803-41-6 C₃₈H₅₃NO₅Si 
• 105880-45-3 C₂₅H₄₂O₄Si 
• 105880-44-2 C₂₅H₄₂O₄Si 
• 105880-66-8 RS₉₃₅₂₀ 
• 105880-50-0 4-[(1S,2S,3R,6S)-2-((S)-3-Cyclohexyl-3-hydroxy-prop-1-ynyl)-3-hydroxy-bicyclo[4.2.0]oct-(7E)-ylidene]-butyric acid 
• 105284-21-7 butanoic acid, 4-[(1S,2S,3R,6S)-2-[(3S)-3-cyclohexyl-3-hydroxy-1-propynyl]-3-hydroxybicyclo[4.2.0]oct-7-ylidene]-(4Z) 
• 108147-34-8 (1S,2R,3S,6R)-2-((S)-3-Cyclohexyl-3-hydroxy-prop-1-ynyl)-3-hydroxy-bicyclo[4.2.0]octan-7-one 
• 108147-32-6 (1S,2R,3S,6R)-2-((R)-3-Cyclohexyl-3-hydroxy-prop-1-ynyl)-3-hydroxy-bicyclo[4.2.0]octan-7-one 
• 108147-33-7 (1R,2S,3R,6S)-2-((R)-3-Cyclohexyl-3-hydroxy-prop-1-ynyl)-3-hydroxy-bicyclo[4.2.0]octan-7-one 
• 108104-23-0 (S)-hexahydromandelaldehyde acetate 

Relevant articles and documents

Sc(OTf)3-catalyzed [3 + 2]-cycloaddition of nitrones with ynones

An efficient approach to access functionalized (2,3-dihydroisoxazol-4-yl) ketones has been developed by reacting nitrones 4 with ynones 7 or terminal ynones 10 in a one-pot fashion. The reaction went through a formal Sc(OTf)3-catalyzed [3 + 2]-cycloaddition process to generate a number of functionalized (2,3-dihydroisoxazol-4-yl) ketones 11aa-11aw, 11ba-11la and 12aa-12ae in moderate to good yields. This journal is

Gem-Digold Acetylide Complexes for Catalytic Intermolecular [4 + 2] Cycloaddition: Having Two Gold Centers Is Better for Asymmetric Catalysis

Gold(I)-catalyzed highly enantioselective intermolecular [4 + 2] cycloaddition is shown with ynones and cyclohexadiene. Various bicyclo[2.2.2]octadiene derivatives are produced in high yields (up to 99%) with good enantioselectivity (up to 96% ee). Key to the success is generation of the gem-digold terminal alkyne as a catalytic on-cycle species. As proof of the gem-digold catalysis, a positive nonlinear effect is clarified between the ee's of the ligand and the cycloadduct.

Mild propargylic oxidation using a diacetoxyiodobenzene/tert-butyl hydroperoxide protocol

A mild propargylic oxidation of alkynes is reported using a diacetoxyiodobenzene/tert-butyl hydroperoxide (DIB/TBHP) protocol. The reactions proceed smoothly at 0 °C and a number of α,β-unsaturated alkynoic ketones are obtained.