7560-86-3

Basic information

• Product Name: 1-cyclohexyl-4-methylpiperazine
• Synonyms: 1-cyclohexyl-4-methylpiperazine
• CAS NO: 7560-86-3
• Molecular Weight: 182.309
• Mol File: 7560-86-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-cyclohexyl-4-methylpiperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-cyclohexyl-4-methylpiperazine(7560-86-3)
• EPA Substance Registry System: 1-cyclohexyl-4-methylpiperazine(7560-86-3)

Safety Data

• Hazardous Substances Data: 7560-86-3(Hazardous Substances Data)

Upstream product

• 3074-43-9 1-methyl-4-phenylpiperazine 
• 109-01-3 1-methyl-piperazine 
• 108-94-1 cyclohexanone 
• 108-93-0 cyclohexanol 

Relevant articles and documents

METHOD OF PRODUCING TERTIARY AMINE OR TERTIARY AMINE DERIVATIVE

PROBLEM TO BE SOLVED: To provide a method of producing tertiary amine or tertiary amine derivative with high selectivity. SOLUTION: In the method of producing tertiary amine or tertiary amine derivative, a reaction system including: an organic chemical raw material containing at least one kind of group selected from -NH2, -NH2 HCl, >NH and >NH HCl, a nitrogen atom contained in the group bounding to a carbon atom; aliphatic alcohol having 1 to 20 carbon atoms; and a catalyst where a carrier containing titanium oxide carries a silver component (metal silver or silver compound), is irradiated with light, and the group in the organic compound raw material is converted to -NR02 or >NR0, ( R0 is an aliphatic hydrocarbon group having 1 to 20 carbon atoms derived from the aliphatic alcohol). The percentage content of the silver in the catalyst is 0.5 to 10 mass% with respect to the titanium oxide. COPYRIGHT: (C)2015,JPOandINPIT

Ruthenium-catalyzed /V-alkylation of amines and sulfonamides using borrowing hydrogen methodology

The alkylation of amines by alcohols has been achieved using 0.5 mol percent [Ru(p-cymene)CI2]2 with the bidentate phosphines dppf or DPEphos as the catalyst. Primary amines have been converted into secondary amines, and secondary amines into tertiary amines, including the syntheses of Piribedil, Tripelennamine, and Chlorpheniramine. A/-Heterocyclization reactions of primary amines are reported, as well as alkylation reactions of primary sulfonamides. Secondary alcohols requiremore forcing conditions than primary alcohols but are still effective a lkylating agents in the presence of this catalyst.