75601-33-1

Basic information

• Product Name: 4-(2-Thienyl)benzoic acid ethyl ester
• Synonyms: 4-(2-Thienyl)benzoic acid ethyl ester
• CAS NO: 75601-33-1
• Molecular Formula: C₁₃H₁₂O₂S
• Molecular Weight: 0
• Mol File: 75601-33-1.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(2-Thienyl)benzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Thienyl)benzoic acid ethyl ester(75601-33-1)
• EPA Substance Registry System: 4-(2-Thienyl)benzoic acid ethyl ester(75601-33-1)

Safety Data

• Hazardous Substances Data: 75601-33-1(Hazardous Substances Data)

Upstream product

• 188290-36-0 thiophene 
• 7334-36-3 4,4'-triazenediyl-di-benzoic acid diethyl ester 
• 853955-72-3 [2-(hydroxymethyl)phenyl]dimethyl(2-thienyl)silane 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 96-43-5 2-thienyl chloride 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 197009-90-8 2-(hydroxydimethylsilyl)thiophene 
• 94-09-7 p-aminoethylbenzoate 
• 1003-09-4 2-bromothiophene 
• 54663-78-4 tributyl(thien-2-yl)stannane 
• 98634-20-9 ethyl 4-(tosyloxy)benzoate 
• 451-46-7 4-fluorobenzoic acid ethyl ester 
• 1309233-77-9 C₁₃H₂₄O₃STi 
• 6165-68-0 thiophene boronic acid 

Downstream Products

• 134831-51-9 4-(5-Tetradecyl-thiophen-2-yl)-benzoic acid 3-fluoro-4-octyloxy-phenyl ester 
• 134831-50-8 4-(5-Dodecyl-thiophen-2-yl)-benzoic acid 3-fluoro-4-octyloxy-phenyl ester 
• 134831-49-5 4-(5-Decyl-thiophen-2-yl)-benzoic acid 3-fluoro-4-octyloxy-phenyl ester 
• 134831-48-4 4-(5-Nonyl-thiophen-2-yl)-benzoic acid 3-fluoro-4-octyloxy-phenyl ester 
• 134831-47-3 3-fluoro-4-n-octyloxyphenyl 4-(5-n-octyl-2-thienyl)benzoate 
• 134831-46-2 4-(5-Heptyl-thiophen-2-yl)-benzoic acid 3-fluoro-4-octyloxy-phenyl ester 
• 134831-45-1 4-(5-Hexyl-thiophen-2-yl)-benzoic acid 3-fluoro-4-octyloxy-phenyl ester 
• 134831-44-0 4-(5-Pentyl-thiophen-2-yl)-benzoic acid 3-fluoro-4-octyloxy-phenyl ester 
• 134831-43-9 4-(5-Butyl-thiophen-2-yl)-benzoic acid 3-fluoro-4-octyloxy-phenyl ester 
• 282722-62-7 4-(5-Octyl-thiophen-2-yl)-benzoic acid 

Relevant articles and documents

Organozinc-mediated direct cross-coupling under microwave irradiation

We report a direct cross-coupling reaction between (het)aryl pivalates/tosylates and di(het)arylzinc species in 2-methyltetrahydrofuran/N-methyl pyrrolidone (1:1), which occurs via C–O bond cleavage under microwave irradiation. The reaction takes place smoothly in short reaction times without the addition of any catalyst or ligand. The reaction is suitable for a broad scope of substrates and exhibits good functional group compatibility, utilizes a simple work-up procedure, and gives the desired products in high purity.

Perylenequinonoid-catalyzed photoredox activation for the direct arylation of (het)arenes with sunlight

Naturally occurring perylenequinonoid pigments (PQPs) have attracted considerable attention owing to their excellent properties of photosensitization. They have been widely investigated as an aspect of photophysics and photobiology. However, their applications in photocatalysis are yet to be explored. We report here that sunlight along with 1 mol% cercosporin, which is one of the perylenequinonoid pigments, catalyzes the direct C-H bond arylation of (het)arenes by a photoredox process with good regioselectivity and broad functional group compatibility. Furthermore, a gram-scale reaction with great conversions of substrates was achieved even by a cercosporin-containing supernatant without organic solvent extraction and purification after liquid fermentation. Thus we set up a bridge between microbial fermentation and organic photocatalysis for chemical reactions in a sustainable, environmentally friendly manner.

Mechanochemical Activation of Zinc and Application to Negishi Cross-Coupling

A form independent activation of zinc, concomitant generation of organozinc species and engagement in a Negishi cross-coupling reaction via mechanochemical methods is reported. The reported method exhibits a broad substrate scope for both C(sp3)–C(sp2) and C(sp2)–C(sp2) couplings and is tolerant to many important functional groups. The method may offer broad reaching opportunities for the in situ generation organometallic compounds from base metals and their concomitant engagement in synthetic reactions via mechanochemical methods.