75605-52-6 Usage
Description
Benzyl-(1-amino-3-chloro-2-propanol) is a chemical compound characterized by the presence of a benzyl group attached to an amino alcohol functional group, which includes a chlorine atom. benzyl-(1-amino-3-chloro-2-propanol) is recognized for its versatile applications in the synthesis of pharmaceuticals and organic compounds, primarily serving as a chiral auxiliary. Its unique structure endows it with antimicrobial, antiviral, and antitumor properties, making it a valuable component in the development of new materials and as a reagent in organic chemistry reactions.
Uses
Used in Pharmaceutical Synthesis:
Benzyl-(1-amino-3-chloro-2-propanol) is utilized as a chiral auxiliary in the synthesis of pharmaceuticals, contributing to the production of enantiomerically pure compounds, which is crucial for ensuring the desired biological activity and minimizing potential side effects.
Used in Organic Compounds Synthesis:
benzyl-(1-amino-3-chloro-2-propanol) also serves as a building block in the synthesis of various organic compounds, facilitating the creation of complex molecular structures with specific stereochemistry.
Used in Antimicrobial Applications:
Due to its antimicrobial properties, benzyl-(1-amino-3-chloro-2-propanol) is employed in applications aimed at inhibiting the growth of harmful microorganisms, which can be beneficial in medical, industrial, and environmental contexts.
Used in Antiviral Applications:
The antiviral characteristics of benzyl-(1-amino-3-chloro-2-propanol) make it a potential candidate for the development of treatments against viral infections, offering a new avenue for therapeutic intervention.
Used in Antitumor Applications:
Its antitumor properties position benzyl-(1-amino-3-chloro-2-propanol) as a component in the development of cancer therapies, potentially contributing to the inhibition of tumor growth and the advancement of novel treatment strategies.
Used in Material Development:
benzyl-(1-amino-3-chloro-2-propanol)'s potential applications extend to the development of new materials, where its unique structural features may impart specific properties to the materials, such as improved stability or reactivity.
Used in Organic Chemistry Reactions:
Benzyl-(1-amino-3-chloro-2-propanol) also functions as a reagent in organic chemistry reactions, where it can facilitate or enhance the synthesis of target molecules, contributing to the advancement of chemical research and the discovery of new compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 75605-52-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,6,0 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 75605-52:
(7*7)+(6*5)+(5*6)+(4*0)+(3*5)+(2*5)+(1*2)=136
136 % 10 = 6
So 75605-52-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H14ClNO/c11-6-10(13)8-12-7-9-4-2-1-3-5-9/h1-5,10,12-13H,6-8H2
75605-52-6Relevant articles and documents
Green Regio- and Enantioselective Aminolysis Catalyzed by Graphite and Graphene Oxide under Solvent-Free Conditions
Acocella, Maria Rosaria,D'Urso, Luciana,Maggio, Mario,Guerra, Gaetano
, p. 1915 - 1920 (2016/07/06)
The ring-opening reactions of epoxides with amines were efficiently and regioselectively catalyzed by high-surface-area graphite and graphene oxide under metal-free and solvent-free conditions. For epoxides without aryl groups, catalytic activity was observed only for graphene oxide, and hence, the activity must have been due to its acidic groups. For styrene oxide, instead, graphite and graphene oxide exhibited rather similar catalytic activities, and hence, the activity was mainly due to activation of the electrophilic epoxide by π-stacking interactions with the graphitic π system. The described aminolysis procedure is green and cheap because the catalyst can be recovered and recycled without loss of efficiency. Moreover, these heterogeneous catalysts exert high stereoselective control in the presence of nonracemic epoxides and provide chiral β-amino alcohols with enantiomeric excess values up to 99 %.
Highly regioselective and efficient synthesis of aminoepoxides by ring closure of aminohalohydrins mediated by KF-Celite
Pace, Vittorio,Hoyos, Pilar,Sinisterra, José Vicente,Alcántara, Andrés R.,Holzer, Wolfgang
supporting information; experimental part, p. 1831 - 1834 (2011/09/16)
The regioselective synthesis of several aminoepoxides has been achieved without observing any trace of azetidinols, which are usually reported as the exclusive reaction products when aminohalohydrins are treated with bases. The use of the mild supported base KF-Celite in refluxing acetonitrile is crucial for modulating the excellent regioselectivity observed. Georg Thieme Verlag Stuttgart . New York.
DMAP-catalyzed synthesis of 2-oxazolidinones from corresponding halohydrins using KOCN/DMF
Chinnam Naidu,Ravi Babu,Gangaiah,Mukkanti,Madhusudhan
experimental part, p. 1226 - 1229 (2010/04/23)
We report facile and simple synthesis of a variety of 2-oxazolidinones from the corresponding halohydrins by reaction with KOCN in DMF catalyzed by DMAP. DMAP and temperature play key roles in enriching the yield of 2-oxazolidinones. A few examples in this Letter are applicable to pharmaceutically important processes.
