75606-47-2Relevant articles and documents
(Dialkyl-1,1 propene-2-yl)-2 thiazolidines: synthese regioselective et hydrolyse en aldehydes β-ethyleniques α,α-disubstitues
Laduranty, Joelle,Barbot, Francis,Miginiac, Leone
, p. 850 - 855 (2007/10/02)
We describe a convenient method leading to α,α-disubstituted β-ethylenic aldehydes by hydrolysis of 2-(1,1-dialkyl 2-propenyl) thiazolidines, which are easily prepared by reaction between gem-disubstituted allylic Grignard reagents and 4,5-dihydrothiazoles.
Synthesis and radiopharmacological study of unsaturated derivatives of cysteamine
Mesnard,Miginiac,Fatome,et al.
, p. 247 - 252 (2007/10/02)
Synthesis of many unsaturated compounds derivated from cysteamine has been carried out in the three series : β-aminothioethers, β-aminothiols and thiazolidines. These products are more or less toxic, compared to corresponding saturated derivates. They generally have a higher radioprotective activity. The three most effective have a dose reduction factor equivalent to that of cysteamine, two of them having a lower toxicity.