75611-06-2

Basic information

• Product Name: 2-BENZO[B]FURAN-3-YLETHANOL
• Synonyms: 2-BENZO[B]FURAN-3-YLETHANOL;2-Benzo[b]furan-3-ylethanol 95%;2-(Benzofuran-3-yl)ethanol;2-(1-Benzofuran-3-yl)ethan-1-ol, 2-(Benzo[b]furan-3-yl)ethan-1-ol;3-(2-Hydroxyethyl)benzo[b]furan 95%
• CAS NO: 75611-06-2
• Molecular Formula: C₁₀H₁₀O₂
• Molecular Weight: 162.19
• Mol File: 75611-06-2.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 279.793 °C at 760 mmHg
• Flash Point: 123.015 °C
• Appearance: /
• Density: 1.187 g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.612
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.78±0.10(Predicted)
• CAS DataBase Reference: 2-BENZO[B]FURAN-3-YLETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZO[B]FURAN-3-YLETHANOL(75611-06-2)
• EPA Substance Registry System: 2-BENZO[B]FURAN-3-YLETHANOL(75611-06-2)

Safety Data

• Hazardous Substances Data: 75611-06-2(Hazardous Substances Data)

Usage

General Description

2-Benzo[b]furan-3-ylethanol, also known as 3-(2-Furyl)-1-ethanol, is a chemical compound with the molecular formula C10H10O2. It belongs to the organic class of compounds known as benzofurans, which are organic compounds containing a benzene ring fused to a furan ring. Benzofurans are a commonly occurring structure in many pharmaceuticals and natural products. 2-Benzo[b]furan-3-ylethanol shows potential utility in organic synthesis and other chemical applications due to its reactive benzo[b]furan moiety. The properties of this compound, like its structure and stability, are determined by its molecular structure and its specific arrangement of atoms.

InChI:InChI=1/C10H10O2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,11H,5-6H2

Upstream product

• 82156-58-9 benzofuran-3-yl-acetic acid ethyl ester 
• 26278-23-9 methyl 2-(benzofuran-3-yl)acetate 
• 16853-85-3 lithium aluminium tetrahydride 
• 64175-51-5 2-(3-benzofuranyl)acetic acid 
• 40052-96-8 3-pyrrolidin-1-ylbenzofuran 
• 52407-43-9 3-cyanomethylbenzo[b]furan 
• 7169-34-8 3-oxo-2,3-dihydrobenzo[b]furan 
• 881015-10-7 (E)-4-(2-Iodo-phenoxy)-but-2-enoic acid ethyl ester 
• 533-58-4 2-Iodophenol 
• 160194-30-9 1-tert-butyldimethylsilyl-4-(tert-butyldimethylsilyloxy)but-1-yne 

Downstream Products

• 136229-46-4 2-(2-hydroxyphenyl)anthraquinone 
• 660438-68-6 N-[(4aR,6R,7R,8R,8aS)-6-(2-Benzofuran-3-yl-ethoxy)-8-hydroxy-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl]-2-fluoro-5-nitro-benzamide 
• 850249-72-8 (2R,3R,4R,5R,6R)-6-(5-Azido-pentyloxymethyl)-2-(2-benzofuran-3-yl-ethoxy)-4,5-bis-benzyloxy-tetrahydro-pyran-3-ol 
• 26278-25-1 2-(benzofuran-3-yl)ethyl 4-methylbenzenesulfonate 

Relevant articles and documents

Synthesis and antidepressant-like activity of novel aralkyl piperazine derivatives targeting SSRI/5-HT1A/5-HT7

A series of novel aralkyl piperazine derivatives were synthesized, and evaluated for their serotonin reuptake inhibitory and 5-HT1A/5-HT7 receptors affinities activity. Antidepressant activities in vivo of the compounds were screened using the forced swimming test (FST) and tail suspension test (TST). The results indicated that compounds 21k (RUI, IC50 = 31 nM; 5-HT1A, 5-HT7, ki = 62, 12 nM) and 21n (RUI, IC50 = 25 nM; 5-HT1A, 5-HT7, ki = 28, 3.3 nM) exhibited high affinities for the 5-HT1A/5-HT7 receptors coupled with potent serotonin reuptake inhibition. Specifically, the most promising compound 21n possessed a good oral pharmacokinetic properties and an acceptable hERG profile, and showed potent antidepressant-like effect in the FST and TST models.

BENZOFURAN AMIDES AND HETEROAROMATIC ANALOGUES THEREOF FOR USE IN THERAPY

The present invention relatesto a pharmaceutical composition comprising acompound of the formula Ias described belowor a tautomeror a pharmaceutically acceptable salt thereof; to the compound of the formula Ias described below or a tautomer or a phar- mac

OPIOID RECEPTOR MODULATORS

The present invention provides a compound having the structure wherein A is a ring structure, with or without substitution; X1 is C or N; X2 is N, 0, or S; Y1 is H, -(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alky